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Gökhan S. Hotamışlıgil

Harvard University · US
Area of research
Epidemiology · Physiology
Research interest
Research interests include Adipokines, Inflammation, and Metabolic Diseases, Adipose Tissue and Metabolism, Peroxisome Proliferator-Activated Receptors, and Endoplasmic Reticulum Stress and Disease.
h-index
112
citations
94,153
works
243
NIH funding
primary concept
email

Recent publications

The time is now: accounting for time-of-day effects to improve reproducibility and translation of metabolism research
Nature Metabolism 2025cited by 18position: middledoi
Adiposity, immunity, and inflammation: interrelationships in health and disease: a report from 24th Annual Harvard Nutrition Obesity Symposium, June 2023
American Journal of Clinical Nutrition 2024cited by 15position: middledoi
Control of cholesterol-induced adipocyte inflammation by the Nfe2l1-Atf3 pathway
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 1position: middledoi
Endothelial-derived FABP4 constitutes the majority of basal circulating hormone and regulates lipolysis-driven insulin secretion
JCI Insight 2023cited by 21position: lastdoi
Author Correction: A central role for JNK in obesity and insulin resistance
Nature 2023cited by 8position: lastdoi
Regulation of liver subcellular architecture controls metabolic homeostasis
Nature 2022cited by 124position: lastdoi
Metabolic Messengers: tumour necrosis factor
Nature Metabolism 2021cited by 406position: lastdoi
Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H<sub>2</sub>O<sub>2</sub> production in heart and skeletal muscle mitochondria
FEBS Letters 2020cited by 29position: lastdoi
The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans
Science Translational Medicine 2019cited by 282position: lastdoi
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
Nature Medicine 2018cited by 216position: lastdoi
Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism
Nature 2017cited by 695position: middledoi
The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue
Nature Medicine 2017cited by 440position: middledoi
Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment
Journal of Lipid Research 2016cited by 476position: lastdoi
Long-Term Calorie Restriction Enhances Cellular Quality-Control Processes in Human Skeletal Muscle
Cell Reports 2016cited by 163position: middledoi
Leptin Deficiency Shifts Mast Cells toward Anti-Inflammatory Actions and Protects Mice from Obesity and Diabetes by Polarizing M2 Macrophages
Cell Metabolism 2015cited by 135position: middledoi
Potential role for snoRNAs in PKR activation during metabolic stress
Proceedings of the National Academy of Sciences 2015cited by 114position: middledoi
Coordinated regulation of protein synthesis and degradation by mTORC1
Nature 2014cited by 358position: middledoi
Restoration of the Unfolded Protein Response in Pancreatic β Cells Protects Mice Against Type 1 Diabetes
Science Translational Medicine 2013cited by 308position: lastdoi
Adipocyte Lipid Chaperone aP2 Is a Secreted Adipokine Regulating Hepatic Glucose Production
Cell Metabolism 2013cited by 267position: lastdoi
trans-Palmitoleic acid, other dairy fat biomarkers, and incident diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA)
American Journal of Clinical Nutrition 2013cited by 267position: middledoi
The Role of Adipocyte XBP1 in Metabolic Regulation during Lactation
Cell Reports 2013cited by 82position: lastdoi
Turning off the inflammatory, but not the metabolic, flames
Nature Medicine 2013cited by 67position: lastdoi
Novel role of PKR in inflammasome activation and HMGB1 release
Nature 2012cited by 760position: middledoi
The Role of Endoplasmic Reticulum in Hepatic Lipid Homeostasis and Stress Signaling
Cell Metabolism 2012cited by 545position: lastdoi
Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders
Proceedings of the National Academy of Sciences 2012cited by 174position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Karen Inouye · Center for Disease Dynamics, Economics & Policy7 papers (2012–2023)Alexander Bartelt · Harvard University4 papers (2017–2024)M. Furkan Burak · Brigham and Women's Hospital3 papers (2013–2024)Scott B. Widenmaier · University of Saskatchewan3 papers (2014–2024)Gürol Tuncman · Harvard University3 papers (2013–2023) · 3 papers (2017–2024)Grace Yankun Lee · Harvard University2 papers (2022–2023)Ling Yang · University of Iowa2 papers (2013–2016) · 2 papers (2012–2015)Oliver T. Bruns† · Nationales Centrum für Tumorerkrankungen Dresden2 papers (2018–2024)Cem Z. Görgün · BioNTech (United States)2 papers (2012–2023)Ana Paula Arruda · Chan Zuckerberg Biohub San Francisco2 papers (2018–2022)Renata L. S. Gonçalves · National Institute of Allergy and Infectious Diseases2 papers (2018–2020)Yu‐Hua Tseng · University of Connecticut2 papers (2017–2018)Matthew D. Lynes · University of Connecticut2 papers (2017–2018) · 2 papers (2017–2018)Güneş Parlakgül · University of California, Berkeley2 papers (2018–2022)Matthias Blüher · Boehringer Ingelheim (China)2 papers (2017–2024)Meric Erikci Ertunc · Massachusetts Institute of Technology2 papers (2013–2016) · 2 papers (2013–2013)