← back to search

Sara B. Linker

Pfizer (United States) · US
Area of research
Molecular Biology · Plant Science
Research interest
Research interests include Chromosomal and Genetic Variations, Genomic variations and chromosomal abnormalities, Single-cell and spatial transcriptomics, and Epigenetics and DNA Methylation.
h-index
27
citations
4,089
works
69
NIH funding
primary concept
email

Recent publications

Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation
Cell Reports 2024cited by 22position: middledoi
Control-independent mosaic single nucleotide variant detection with DeepMosaic
Nature Biotechnology 2023cited by 39position: middledoi
Genomic data resources of the Brain Somatic Mosaicism Network for neuropsychiatric diseases
Scientific Data 2023cited by 5position: middledoi
Author Correction: Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia
Nature Neuroscience 2023cited by 0position: middledoi
Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing
Nature Neuroscience 2023cited by 0position: middledoi
Analysis of somatic mutations in 131 human brains reveals aging-associated hypermutability
Science 2022cited by 71position: middledoi
Somatic mosaicism reveals clonal distributions of neocortical development
Nature 2022cited by 61position: middledoi
Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients
npj Parkinson s Disease 2022cited by 61position: middledoi
Human-specific regulation of neural maturation identified by cross-primate transcriptomics
Current Biology 2022cited by 28position: firstdoi
The role of retrotransposable elements in ageing and age-associated diseases
Nature 2021cited by 427position: middledoi
The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing
Nature Neuroscience 2021cited by 133position: middledoi
Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons
Science 2021cited by 117position: middledoi
Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients
Molecular Psychiatry 2021cited by 75position: middledoi
Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia
Nature Neuroscience 2021cited by 36position: middledoi
Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism
Proceedings of the National Academy of Sciences 2020cited by 67position: middledoi
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells
eLife 2019cited by 138position: middledoi
Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons
Nature Protocols 2016cited by 508position: middledoi
Sequencing, identification and mapping of primed L1 elements (SIMPLE) reveals significant variation in full length L1 elements between individuals
BMC Genomics 2015cited by 40position: middledoi
KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency
Stem Cell Reports 2015cited by 38position: middledoi

Grants

NSF East Asia and Pacific Summer Institute (EAPSI) for FY 2013 in Japan
NSF1310710$702013–2014PIRePORTER

Frequent collaborators

Fred H. Gage · Salk Institute for Biological Studies7 papers (2016–2024)Lynne Randolph‐Moore · Salk Institute for Biological Studies3 papers (2019–2022)Renata Santos · Salk Institute for Biological Studies3 papers (2019–2022)Ana P. D. Mendes · Universidade Brasil3 papers (2019–2022)Iñigo Narvaiza · Salk Institute for Biological Studies2 papers (2019–2022)Ruth Oefner · Salk Institute for Biological Studies2 papers (2019–2022)Grace Chou · Salk Institute for Biological Studies2 papers (2019–2021)Nasun Hah · Fleet Science Center2 papers (2019–2021)Simon T. Schafer · Technical University of Munich2 papers (2021–2024)Stephen L. Helfand · Brown University1 papers (2021–2021)Eunice Mejia · Salk Institute for Biological Studies1 papers (2022–2022)Callie Fredlender · Salk Institute for Biological Studies1 papers (2019–2019) · 1 papers (2015–2015)Benjamin Lacar · University of California, San Francisco1 papers (2016–2016)Yeni Kim · Salk Institute for Biological Studies1 papers (2021–2021)Galina Erikson · Max Planck Institute of Immunobiology and Epigenetics1 papers (2021–2021)Martin Alda · McGill University Health Centre1 papers (2021–2021)Bilal E. Kerman · Salk Institute for Biological Studies1 papers (2019–2019)Son Pham · Baylor College of Medicine1 papers (2016–2016)John R. Kelsoe · Inserm1 papers (2021–2021)