Area of research
Molecular Biology · Immunology
Research interest
Research interests include Atherosclerosis and Cardiovascular Diseases, SARS-CoV-2 and COVID-19 Research, Protein Structure and Dynamics, and Monoclonal and Polyclonal Antibodies Research.
Design of high-affinity binders to immune modulating receptors for cancer immunotherapy
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies
De novo design of luciferases using deep learning
Top-down design of protein architectures with reinforcement learning
Design of protein-binding proteins from the target structure alone
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice
Isoform-specific inhibition of FGFR signaling achieved by a de-novo-designed mini-protein
Rapid and Sensitive Detection of Antigen from SARS-CoV-2 Variants of Concern by a Multivalent Minibinder-Functionalized Nanomechanical Sensor
De novo design of modular and tunable protein biosensors
Ultrapotent miniproteins targeting the SARS-CoV-2 receptor-binding domain protect against infection and disease
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
Functional expression and characterization of the envelope glycoprotein E1E2 heterodimer of hepatitis C virus