Area of research
Endocrinology, Diabetes and Metabolism · Cardiology and Cardiovascular Medicine
Research interest
Professor of Clinical Epidemiology, University Medical Center Utrecht, and Distinguished University Professor International Health Sciences and Global Health, Utrecht University. Chair, Julius Global Health (www.globalhealth.eu). Founder Elevate on-line academic education platform in Life Sciences (www.elevatehealth.eu). He has been a (principal) investigator in many large-scale epidemiologic studies and randomized intervention trials relating to the prevention and treatment of cardiovascular, cardiometabolic, and cardiorenal disease. In addition he works on the principles and methods of prediction research and trial design. Member of the board, and chair Global Affairs Committee, European Society of Cardiology. Past President European Association of Preventive Cardiology.
Transforming clinical decisions with artificial intelligence: the HYPERMARKER project.
Sample size considerations to assess sex-related treatment effects.
Machine learning-enabled systematic review on coded healthcare data in heart failure research.
Metabolic dysfunction-associated steatotic liver disease and the heart.
2024 Revision of the level of evidence grading system for ESC clinical practice guideline recommendations II: diagnostic tests and prediction models
Sex Differences in Acute Coronary Syndromes: A Scoping Review Across the Care Continuum
2024 Revision of the level of evidence grading system for ESC clinical practice guideline recommendations II: diagnostic tests and prediction models.
Mendelian Randomisation: Concepts, Opportunities, Challenges, and Future Directions
Bringing Trial Activities to Participants-The Trials@Home RADIAL Proof-of-Concept Trial Investigating Decentralization of Trials.
Sex Differences in Acute Coronary Syndromes: A Scoping Review Across the Care Continuum.
Recruiting and Consenting Decentralized Clinical Trial Participants-Learnings from the Trials@Home RADIAL Proof-of-Concept Trial.
Selecting and Preparing Clinical Sites for the Successful Conduct of Decentralized Clinical Trial Activities-Findings From the Trials@Home RADIAL Proof-of-Concept Trial.
Mendelian Randomisation: Concepts, Opportunities, Challenges, and Future Directions.
Uptitration of statin therapy in women and men: a population-based cohort study.
Smoking as a Risk Factor for Cardiovascular Disease in Females and Males: Observational and Mendelian Randomisation Analyses in the UK Biobank.
The Association Between HIV-Related Stigma, ART Adherence, and Cardiovascular Disease Risk in People Living With HIV.
Metabolic dysfunction-associated steatotic liver disease and cardiovascular risk factors in rheumatoid arthritis.
Determinants, barriers, and facilitators of healthcare access for patients with hypertension in rural Ghana: applying the Andersen-Newman model of healthcare utilization.
The association of HIV status and depressive symptoms in the Ndlovu Cohort study.
Long-Term Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination for the Treatment of Hypertension.
Translation and validation of the Swahili pediatric quality of life family impact module for caregivers of children with congenital heart disease.
Prevalence of Liver Steatosis and Fibrosis Assessed by Transient Elastography in a High Cardiovascular-Risk Outpatient Cohort Including T1DM and T2DM Patients
Ethnic and socioeconomic inequalities in air pollution exposure: a cross-sectional analysis of nationwide individual-level data from the Netherlands
Consumer wearable devices for evaluation of heart rate control using digoxin versus beta-blockers: the RATE-AF randomized trial
Efficacy and safety of a novel low-dose triple single-pill combination of telmisartan, amlodipine and indapamide, compared with dual combinations for treatment of hypertension: a randomised, double-blind, active-controlled, international clinical trial
Efficacy and Safety of a Novel Low-Dose Triple Single-Pill Combination Compared With Placebo for Initial Treatment of Hypertension
Impact of green space exposure on blood pressure in Guangzhou, China: Mediation by air pollution, mental health, physical activity, and weight status
Federated learning as a smart tool for research on infectious diseases
Epidemiology and risk factors for hyperkalaemia in heart failure.
Community-Based Strategies to Improve Health-Related Outcomes in People Living With Hypertension in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis