Area of research
Genetics · Psychiatry and Mental health
Research interest
Research interests include Genetic Associations and Epidemiology, Schizophrenia research and treatment, Eating Disorders and Behaviors, and Genetics and Neurodevelopmental Disorders.
Genetic basis of early onset and progression of type 2 diabetes in South Asians
Genetic architecture of routinely acquired blood tests in a British South Asian cohort
Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia
A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts
Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing
DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Genetic underpinnings of sociability in the general population
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions
Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models
A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Expression-based drug screening of neural progenitor cells from individuals with schizophrenia
Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain
Age at first birth in women is genetically associated with increased risk of schizophrenia
Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia
Epilepsy-associated GRIN2A mutations reduce NMDA receptor trafficking and agonist potency – molecular profiling and functional rescue
Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity
Genetics of schizophrenia: A consensus paper of the WFSBP Task Force on Genetics
Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes
Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders
An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation
Analysis of Intellectual Disability Copy Number Variants for Association With Schizophrenia
Translating genome-wide association findings into new therapeutics for psychiatry
Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia
Consensus paper of the WFSBP Task Force on Genetics: Genetics, epigenetics and gene expression markers of major depressive disorder and antidepressant response
Microduplications at the pseudoautosomal <i>SHOX</i> locus in autism spectrum disorders and related neurodevelopmental conditions
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways