Area of research
Oncology · Infectious Diseases
Research interest
Research interests include CAR-T cell therapy research, Immune Cell Function and Interaction, SARS-CoV-2 and COVID-19 Research, and COVID-19 Clinical Research Studies.
Systematic single amino acid affinity tuning of CD229 CAR T cells retains efficacy against multiple myeloma and eliminates on-target off-tumor toxicity
Low-affinity CAR T cells exhibit reduced trogocytosis, preventing rapid antigen loss, and increasing CAR T cell expansion
Roadmap to affinity-tuned antibodies for enhanced chimeric antigen receptor T cell function and selectivity
CD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide