Michael E. DeBakey VA Medical Center · US
Area of research
Orthopedics and Sports Medicine · Genetics
Research interest
Research interests include Bone health and osteoporosis research, Estrogen and related hormone effects, Bone health and treatments, and Hormonal and reproductive studies.
Lifestyle Intervention Therapy Modulates Global DNA Methylation and Adipogenic Gene Expression in Severely Obese Hypogonadal Men.
Adverse effect of obesity and dysglycemia on bone microarchitecture and strength in youth: sex-related differences.
Metabolic Effects of Testosterone Added to Intensive Lifestyle Intervention in Older Men With Obesity and Hypogonadism.
PRDM16 Enhances Osteoblastogenic RUNX2 via Canonical WNT10b/β-CATENIN Pathway in Testosterone-Treated Hypogonadal Men.
Obesity and Skeletal Fragility.
Testosterone Therapy Effects on Bone Mass and Turnover in Hypogonadal Men with Type 2 Diabetes
Testosterone Therapy Effects on Bone Mass and Turnover in Hypogonadal Men with Type 2 Diabetes.
Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss
Fat Mass Follows a U-Shaped Distribution Based on Estradiol Levels in Postmenopausal Women
Adipocytes ESR1 Expression, Body Fat and Response to Testosterone Therapy in Hypogonadal Men Vary According to Estradiol Levels
Hypogonadal men with type 2 diabetes mellitus have smaller bone size and lower bone turnover
Hypogonadal Men with Higher Body Mass Index have Higher Bone Density and Better Bone Quality but Reduced Muscle Density
High aromatase activity in hypogonadal men is associated with higher spine bone mineral density, increased truncal fat and reduced lean mass
Genetic polymorphism at Val80 (rs700518) of the CYP19A1 gene is associated with body composition changes in women on aromatase inhibitors for ER (+) breast cancer
Increasing Adiposity Is Associated With Higher Adipokine Levels and Lower Bone Mineral Density in Obese Older Adults
Fat, Muscle, and Bone Interactions in Obesity and the Metabolic Syndrome
Weight loss, exercise or both and cardiometabolic risk factors in obese older adults: results of a randomized controlled trial
Changes in thigh muscle volume predict bone mineral density response to lifestyle therapy in frail, obese older adults
Weight loss in obese older adults increases serum sclerostin and impairs hip geometry but both are prevented by exercise training
Increased 2-hydroxylation of estrogen is associated with lower body fat and increased lean body mass in postmenopausal women