Area of research
Immunology · Molecular Biology
Research interest
Research interests include Immune Cell Function and Interaction, Single-cell and spatial transcriptomics, T-cell and B-cell Immunology, and Immunotherapy and Immune Responses.
Subclinical fields of BRAF V600E-mutant melanocytes populate human skin and are enriched around melanoma and naevi.
Feature-preserving manifold approximation and projection to analyze single-cell data.
Coupling dead cell recognition to Fcγ receptors augments anticancer immunity
The GFI1-FOXO1 axis regulates NK cell maturation and function.
CellPhoneDB v5: inferring cell-cell communication from single-cell multiomics data.
Enhancement of anti-sarcoma immunity by NK cells engineered with mRNA for expression of a EphA2-targeted CAR.
scRepertoire 2: Enhanced and efficient toolkit for single-cell immune profiling.
Temporal profiling of human lymphoid tissues reveals coordinated defense against viral challenge.
<i>In Vivo</i> Labeling Resolves Distinct Temporal, Spatial, and Functional Properties of Tumor Macrophages and Identifies Subset-Specific Effects of PD-L1 Blockade
Low-dose interleukin-2 induces clonal expansion of BACH2-repressed effector regulatory T cells following acute coronary syndrome.
Temporal multi-omics analysis of COVID-19 in end-stage kidney disease.
GFI1-driven transcriptional and epigenetic programs maintain CD8<sup>+</sup> T cell stemness and persistence.
In Vivo Labeling Resolves Distinct Temporal, Spatial, and Functional Properties of Tumor Macrophages and Identifies Subset-Specific Effects of PD-L1 Blockade.
<i>dandelionR</i>: Single-cell immune repertoire trajectory analysis in R.
Erratum: Data standards for single-cell RNA-sequencing of paediatric cancer.
Cell-cell interactions as predictive and prognostic markers for drug responses in cancer.
Intestinal challenges shape the polarisation of protective dural memory CD4 T cells
Resolving cDC2 heterogeneity across human cancer atlases
dandelionR: Single-cell immune repertoire trajectory analysis in R
Data standards for single-cell RNA-sequencing of paediatric cancer.
Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity
Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity.
An organotypic atlas of human vascular cells
Venous-plexus-associated lymphoid hubs support meningeal humoral immunity.
Dandelion uses the single-cell adaptive immune receptor repertoire to explore lymphocyte developmental origins.
An organotypic atlas of human vascular cells.
Tumour-retained activated CCR7<sup>+</sup> dendritic cells are heterogeneous and regulate local anti-tumour cytolytic activity.
Single-cell immune repertoire analysis.
TGF-β signalling limits effector function capacity of NK cell anti-tumour immunity in human bladder cancer.
Embracing computational immunology.