Area of research
Immunology · Oncology
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Immune Cell Function and Interaction, Immunotherapy and Immune Responses, and Immune cells in cancer.
Cyclic nucleotide phosphodiesterases as drug targets
A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer.
Cyclic nucleotide phosphodiesterases as drug targets.
β-blocker suppresses both tumoral sympathetic neurons and perivascular macrophages during oncolytic herpes virotherapy.
Abstract 4391: A novel dual inhibitor of RAS and β-catenin signaling with advantages over mutant-specific KRAS inhibitors to escape resistance has robust antitumor efficacy and activates antitumor immunity
Targeting phosphodiesterase 10 unleashes antitumor immunity by inhibiting the RAS-MAPK signaling in cancer cells and myeloid-derived suppressor cells 3553
Calcium nanoparticles target and activate T cells to enhance anti-tumor function
A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer
Calcium nanoparticles target and activate T cells to enhance anti-tumor function.
Novel Celecoxib Derivative, RF26, Blocks Colon Cancer Cell Growth by Inhibiting PDE5, Activating cGMP/PKG Signaling, and Suppressing β-catenin-dependent Transcription
Abstract 2459: ADT-030 is a novel dual-acting RAS/β-catenin inhibitor that potentiates antitumor immunity
1649P Impact of concomitant medications on safety in patients with high-volume metastatic hormone-sensitive prostate cancer (mHSPC) receiving rezvilutamide (Rez) plus androgen-deprivation therapy (ADT): A post-hoc analysis of the randomized phase III CHART trial
Novel sulindac derivatives for colorectal cancer chemoprevention that target cGMP phosphodiesterases to suppress Wnt/β-catenin transcriptional activity
Novel sulindac derivatives for colorectal cancer chemoprevention that target cGMP phosphodiesterases to suppress Wnt/β-catenin transcriptional activity
Abstract 1633: ADT-030, a novel dual-acting RAS and β-catenin inhibitor with robust antitumor activity
Abstract 478: A novel dual-acting RAS/β-catenin inhibitor activates antitumor immunity to potentiate cancer immunotherapy
Abstract 6333: Repurposing NSAIDs for chemo-immunotherapy: mechanisms beyond COX inhibition
Indomethacin-induced oxidative stress enhances death receptor 5 signaling and sensitizes tumor cells to adoptive T-cell therapy
Indomethacin-induced oxidative stress enhances death receptor 5 signaling and sensitizes tumor cells to adoptive T-cell therapy.
Review of: "Orthogonal Gene Engineering Enables CD8+ T Cells to Control Tumors through a Novel PD-1+TOX-indifferent Synthetic Effector State"
Near-infrared light triggered activation of pro-drug combination cancer therapy and induction of immunogenic cell death
Suppression of Colon Tumorigenesis in Mutant <i>Apc</i> Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin
Persistent STAT5 activation reprograms the epigenetic landscape in CD4 <sup>+</sup> T cells to drive polyfunctionality and antitumor immunity
PDE5 and PDE10 inhibition activates cGMP/PKG signaling to block Wnt/β-catenin transcription, cancer cell growth, and tumor immunity
Persistent STAT5 activation reprograms the epigenetic landscape in CD4<sup>+</sup> T cells to drive polyfunctionality and antitumor immunity.
Enhancing anticancer activity of checkpoint immunotherapy by targeting RAS
B7-H3 Promotes Pathogenesis of Autoimmune Disease and Inflammation by Regulating the Activity of Different T Cell Subsets
Vps4A functions as a tumor suppressor by regulating the secretion and uptake of exosomal microRNAs in human hepatoma cells
Depleting tumor-specific Tregs at a single site eradicates disseminated tumors
Depleting tumor-specific Tregs at a single site eradicates disseminated tumors
CSR: EAGER: A Wearable Body Motion Sensing Platform Using Conductive Stretchable Fabric
Quantum Friction, Resonance Problems and New Methods in Geometric Flows
TWC: Small: Collaborative: Towards Energy-Efficient Privacy-Preserving Active Authentication of Smartphone Users
CAREER: Exploiting Sensing Diversity and Conquering Communication Reality to Meet User Requirements in Performance-Critical Wireless Sensor Networks
Quantum Friction, Resonance Problems and New Methods in Geometric Flows
Quantum Friction, Resonance Problems and New Methods in Geometric Flows
CSR: EAGER: Network Traffic Aware Smartphone Energy Savings
NeTS:Small:Collaborative Research:Holistic Transparent Performance Assurance within the Crowded Spectrum
Collaborative Research: Multi-Scale QoS for Body Sensor Networks