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Vadim N. Gladyshev

Harvard University · US
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Area of research
Nutrition and Dietetics · Molecular Biology
Research interest
Research interests include Selenium in Biological Systems, Redox biology and oxidative stress, Trace Elements in Health, and Genetics, Aging, and Longevity in Model Organisms.
h-index
125
citations
54,202
works
780
NIH funding
primary concept
Biology
email

Recent publications

From geroscience to precision geromedicine: Understanding and managing aging
Cell 2025cited by 237position: middledoi
Skin health and biological aging
Nature Aging 2025cited by 32position: middledoi
Evidence for improved DNA repair in the long-lived bowhead whale
Nature 2025cited by 26position: middledoi
A torpor-like state in mice slows blood epigenetic aging and prolongs healthspan
Nature Aging 2025cited by 15position: middledoi
What makes biological age epigenetic clocks tick
Nature Aging 2025cited by 14position: lastdoi
Digital biomarkers of ageing for monitoring physiological systems in community-dwelling adults
The Lancet Healthy Longevity 2025cited by 14position: middledoi
Regeneration leads to global tissue rejuvenation in aging sexual planarians
Nature Aging 2025cited by 13position: middledoi
Invigorating discovery and clinical translation of aging biomarkers
Nature Aging 2025cited by 6position: lastdoi
Extension of lifespan by epicatechin, halofuginone and mitoglitazone in male but not female genetically heterogeneous mice
GeroScience 2025cited by 4position: middledoi
Validation of biomarkers of aging
Nature Medicine 2024cited by 291position: middledoi
Causality-enriched epigenetic age uncouples damage and adaptation
Nature Aging 2024cited by 172position: lastdoi
Challenges and recommendations for the translation of biomarkers of aging
Nature Aging 2024cited by 84position: lastdoi
Nature of epigenetic aging from a single-cell perspective
Nature Aging 2024cited by 70position: lastdoi
PRC2-AgeIndex as a universal biomarker of aging and rejuvenation
Nature Communications 2024cited by 56position: middledoi
Disagreement on foundational principles of biological aging
PNAS Nexus 2024cited by 48position: firstdoi
Epigenetic predictors of species maximum life span and other life-history traits in mammals
Science Advances 2024cited by 32position: middledoi
MethylGPT: a foundation model for the DNA methylome
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 25position: lastdoi
Depletion of loss-of-function germline mutations in centenarians reveals longevity genes
Nature Communications 2024cited by 11position: lastdoi
Loss of epigenetic information as a cause of mammalian aging
Cell 2023cited by 601position: middledoi
Biomarkers of aging for the identification and evaluation of longevity interventions
Cell 2023cited by 584position: lastdoi
Universal DNA methylation age across mammalian tissues
Nature Aging 2023cited by 371position: middledoi
Biological age is increased by stress and restored upon recovery
Cell Metabolism 2023cited by 207position: lastdoi
Chemically induced reprogramming to reverse cellular aging
Aging 2023cited by 129position: middledoi
DNA methylation networks underlying mammalian traits
Science 2023cited by 128position: middledoi
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice
Nature 2023cited by 127position: middledoi
Multi-omic rejuvenation and lifespan extension on exposure to youthful circulation
Nature Aging 2023cited by 123position: middledoi
Author Correction: Universal DNA methylation age across mammalian tissues
Nature Aging 2023cited by 5position: middledoi
Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology
Research Square 2023cited by 1position: middledoi
Rapamycin treatment during development extends life span and health span of male mice and <i>Daphnia magna</i>
Science Advances 2022cited by 76position: lastdoi
Epigenetic aging of the demographically non-aging naked mole-rat
Nature Communications 2022cited by 60position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Steve Horvath · Banyan Biomarkers (United States)11 papers (2019–2025)Vera Gorbunova · University of Rochester Medical Center10 papers (2014–2025)Andrei Seluanov · University of Rochester Medical Center10 papers (2014–2025) · 9 papers (2022–2025) · 5 papers (2015–2022)Jesse R. Poganik · Harvard University5 papers (2022–2025) · 5 papers (2014–2023)Ake T. Lu · Fleet Science Center5 papers (2022–2024)Alexei Lobanov · National Institutes of Health5 papers (2012–2017)Kejun Ying · Broad Institute5 papers (2024–2024) · 4 papers (2012–2022) · 4 papers (2013–2016)Dolph L. Hatfield · National Heart Lung and Blood Institute4 papers (2012–2016)Bohan Zhang · Nanjing Tech University4 papers (2021–2024)Jan Vijg · Montefiore Medical Center3 papers (2014–2018)Vittorio Sebastiano · Stanford University3 papers (2024–2025)Brian K. Kennedy · National University of Singapore3 papers (2020–2025)Andrea B. Maier · Health & Life (Taiwan)3 papers (2020–2025)Alaattin Kaya · Virginia Commonwealth University3 papers (2013–2022) · 3 papers (2022–2023)
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