Area of research
Molecular Biology · Hepatology
Research interest
Research interests include Hepatitis C virus research, CRISPR and Genetic Engineering, Gut microbiota and health, and Clostridium difficile and Clostridium perfringens research.
Unveiling the power of Treg.Sig: a novel machine-learning derived signature for predicting ICI response in melanoma
Influenza virus reassortment patterns exhibit preference and continuity while uncovering cross-species transmission events.
Diversity, Complexity, and Challenges of Viral Infectious Disease Data in the Big Data Era: A Comprehensive Review.
Evaluating the performance of the PREDAC method in flu vaccine recommendations over the past decade (2013–2023)
Deep learning predicts potential reassortments of avian H5N1 with human influenza viruses.
Genome-wide identification of characteristic nucleotide fragments for surveillance and subtype typing of influenza A viruses
Transmission restriction and genomic evolution co-shape the genetic diversity patterns of influenza A virus.
The spatiotemporal analysis of SARS-CoV-2 transmission in China since the termination of the dynamic zero-COVID policy.
Development of PREDAC-H1pdm to model the antigenic evolution of influenza A/(H1N1) pdm09 viruses.
Mapping Genetic Events of SARS-CoV-2 Variants.
Origin and Reversion of Omicron Core Mutations in the Evolution of SARS-CoV-2 Genomes.
One year of SARS-CoV-2 evolution
Herbicide Resistance: Another Hot Agronomic Trait for Plant Genome Editing
One year of SARS-CoV-2 evolution.
Co-mutation modules capture the evolution and transmission patterns of SARS-CoV-2
Co-mutation modules capture the evolution and transmission patterns of SARS-CoV-2.
Progress and Challenge in Computational Identification of Influenza Virus Reassortment.
Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China
Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China.
FluReassort: a database for the study of genomic reassortments among influenza viruses.
Cluster-Transition Determining Sites Underlying the Antigenic Evolution of Seasonal Influenza Viruses.
Protective effect of DHEA on hydrogen peroxide-induced oxidative damage and apoptosis in primary rat Leydig cells
Prevalence of Resistance-Associated Substitutions in HCV NS5A, NS5B, or NS3 and Outcomes of Treatment With Ledipasvir and Sofosbuvir
Dehydroepiandrosterone inhibits cell proliferation and improves viability by regulating S phase and mitochondrial permeability in primary rat Leydig cells
Ledipasvir and sofosbuvir in patients with genotype 1 hepatitis C virus infection and compensated cirrhosis: An integrated safety and efficacy analysis
Safety and tolerability of ledipasvir/sofosbuvir with and without ribavirin in patients with chronic hepatitis C virus genotype 1 infection: Analysis of phase III ION trials
Dehydroepiandrosterone ameliorates H2O2-induced Leydig cells oxidation damage and apoptosis through inhibition of ROS production and activation of PI3K/Akt pathways
Dehydroepiandrosterone-Regulated Testosterone Biosynthesis via Activation of the ERK1/2 Signaling Pathway in Primary Rat Leydig Cells
Ledipasvir and Sofosbuvir for Untreated HCV Genotype 1 Infection
Concordance of sustained virological response 4, 12, and 24 weeks post‐treatment with sofosbuvir‐containing regimens for hepatitis C virus