Area of research
Psychiatry and Mental health · Cellular and Molecular Neuroscience
Research interest
Research interests include Medicine, Epilepsy, Epileptogenesis, Blood–brain barrier, Neuroscience, and Intensive care medicine.
New epilepsy therapies in development
Epilepsy and epileptiform activity in late-onset Alzheimer disease: clinical and pathophysiological advances, gaps and conundrums
The impact of ATP-binding cassette transporters in the diseased brain: Context matters
Prevention of epileptogenesis – are we there yet?
Mammalian models of status epilepticus – Their value and limitations
Of Mice and Men: The Inter-individual Variability of the Brain's Response to Drugs
Antiepileptogenesis and disease modification: Progress, challenges, and the path forward—Report of the Preclinical Working Group of the 2018 NINDS‐sponsored antiepileptogenesis and disease modification workshop
Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?
A face-to-face comparison of claudin-5 transduced human brain endothelial (hCMEC/D3) cells with porcine brain endothelial cells as blood–brain barrier models for drug transport studies
Association of Piriform Cortex Resection With Surgical Outcomes in Patients With Temporal Lobe Epilepsy
Proof-of-concept that network pharmacology is effective to modify development of acquired temporal lobe epilepsy
Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage
Chemokine receptors CCR2 and CX3CR1 regulate viral encephalitis-induced hippocampal damage but not seizures
Blood–Brain Barrier Leakage during Early Epileptogenesis Is Associated with Rapid Remodeling of the Neurovascular Unit
Mechanism of drug extrusion by brain endothelial cells via lysosomal drug trapping and disposal by neutrophils
P11 promoter methylation predicts the antidepressant effect of electroconvulsive therapy
Commonalities in epileptogenic processes from different acute brain insults: Do they translate?
Neuroinflammatory targets and treatments for epilepsy validated in experimental models
Macrophage depletion by liposome-encapsulated clodronate suppresses seizures but not hippocampal damage after acute viral encephalitis
Gene therapy decreases seizures in a model of <i>Incontinentia pigmenti</i>
Advances in the development of biomarkers for epilepsy
2015 ACVIM Small Animal Consensus Statement on Seizure Management in Dogs
Isoflurane prevents acquired epilepsy in rat models of temporal lobe epilepsy
Common data elements and data management: Remedy to cure underpowered preclinical studies
Behavioral differences of male Wistar rats from different vendors in vulnerability and resilience to chronic mild stress are reflected in epigenetic regulation and expression of p11
Infections, inflammation and epilepsy
International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe
International veterinary epilepsy task force consensus proposal: outcome of therapeutic interventions in canine and feline epilepsy
Brain endothelial TAK1 and NEMO safeguard the neurovascular unit
Searching for the Ideal Antiepileptogenic Agent in Experimental Models: Single Treatment Versus Combinatorial Treatment Strategies