Area of research
Small Animals · Dermatology
Research interest
Research interests include Developmental toxicity, Biology, Toxicity, Risk analysis (engineering), Phthalate, and Transcriptome.
Determination of in vitro hepatotoxic potencies of a series of perfluoroalkyl substances (PFASs) based on gene expression changes in HepaRG liver cells
Neuronal differentiation pathways and compound-induced developmental neurotoxicity in the human neural progenitor cell test (hNPT) revealed by RNA-seq
New approach methodologies: A quantitative in vitro to in vivo extrapolation case study with PFASs
Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?
Safer chemicals using less animals: kick-off of the European ONTOX project
Applicability of organ-on-chip systems in toxicology and pharmacology
An update on the hazard of and exposure to diethyl hexyl phthalate (DEHP) alternatives used in medical devices
Workshop on the validation and regulatory acceptance of innovative 3R approaches in regulatory toxicology – Evolution versus revolution
A mode-of-action ontology model for safety evaluation of chemicals: Outcome of a series of workshops on repeated dose toxicity
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes
Rethinking developmental toxicity testing: Evolution or revolution?
Workshop on acceleration of the validation and regulatory acceptance of alternative methods and implementation of testing strategies
A comparison of the embryonic stem cell test and whole embryo culture assay combined with the BeWo placental passage model for predicting the embryotoxicity of azoles
Building a developmental toxicity ontology
Scientific principles for the identification of endocrine-disrupting chemicals: a consensus statement
Comparison of rat and rabbit embryo–fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects
Prenatal Phthalate, Perfluoroalkyl Acid, and Organochlorine Exposures and Term Birth Weight in Three Birth Cohorts: Multi-Pollutant Models Based on Elastic Net Regression
A perspective on the developmental toxicity of inhaled nanoparticles
International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes
Prenatal exposure to environmental chemical contaminants and asthma and eczema in school-age children
Structural bisphenol analogues differentially target steroidogenesis in murine MA-10 Leydig cells as well as the glucocorticoid receptor
Gene Expression Regulation and Pathway Analysis After Valproic Acid and Carbamazepine Exposure in a Human Embryonic Stem Cell-Based Neurodevelopmental Toxicity Assay
Phthalates, perfluoroalkyl acids, metals and organochlorines and reproductive function: a multipollutant assessment in Greenlandic, Polish and Ukrainian men
An adverse outcome pathway framework for neural tube and axial defects mediated by modulation of retinoic acid homeostasis
Exposure‐Based Validation List for Developmental Toxicity Screening Assays
Conazole fungicides inhibit Leydig cell testosterone secretion and androgen receptor activation in vitro
Evaluation of an alternative in vitro test battery for detecting reproductive toxicants in a grouping context
Comparison of osteoblast and cardiomyocyte differentiation in the embryonic stem cell test for predicting embryotoxicity in vivo
Developmental immunotoxicity of chemicals in rodents and its possible regulatory impact
A statistical approach towards the derivation of predictive gene sets for potency ranking of chemicals in the mouse embryonic stem cell test