Area of research
Cell Biology · Molecular Biology
Research interest
Research interests include Cellular transport and secretion, Lipid Membrane Structure and Behavior, Neuroscience and Neuropharmacology Research, and Calcium signaling and nucleotide metabolism.
A versatile nanobody platform for live and super-resolution imaging of synaptic vesicle dynamics and plasticity in rodent and human neurons
Neuronal autophagy in the control of synapse function
Neuronal autophagy controls excitability via ryanodine receptor–mediated regulation of calcium-activated potassium channel function
Control of renal calcium permeability via a tight junctional claudin switch
Phosphatidylinositol 3,5-bisphosphate facilitates axonal vesicle transport and presynapse assembly
Intersectin deficiency impairs cortico-striatal neurotransmission and causes obsessive–compulsive behaviors in mice
An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor
Sulfonated red and far-red rhodamines to visualize SNAP- and Halo-tagged cell surface proteins
Selective endocytosis of Ca <sup>2+</sup> -permeable AMPARs by the Alzheimer’s disease risk factor CALM bidirectionally controls synaptic plasticity
Dissecting the activation of insulin degrading enzyme by inositol pyrophosphates and their bisphosphonate analogs
Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum
Vesicle Clustering in a Living Synapse Depends on a Synapsin Region that Mediates Phase Separation
The axonal endolysosomal and autophagic systems
Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth
Ramping up the autophagy-lysosome system to cope with osmotic stress
A Recurrent Missense Variant in AP2M1 Impairs Clathrin-Mediated Endocytosis and Causes Developmental and Epileptic Encephalopathy
Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling
Mutations in PIK3C2A cause syndromic short stature, skeletal abnormalities, and cataracts associated with ciliary dysfunction
Asymmetric distribution of TLR3 leads to a polarized immune response in human intestinal epithelial cells
Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses
Phosphoinositides in the control of lysosome function and homeostasis
Cellular polarity asymmetrically functionalizes pathogen recognition receptor-mediated intrinsic immune response in human intestinal epithelium cells
Intersectin associates with synapsin and regulates its nanoscale localization and function
Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1
An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling
Phenothiazine‐Derived Antipsychotic Drugs Inhibit Dynamin and Clathrin‐Mediated Endocytosis
Crystal structure of the dynamin tetramer
Multicolor Caged dSTORM Resolves the Ultrastructure of Synaptic Vesicles in the Brain
Probing heterobivalent binding to the endocytic AP-2 adaptor complex by DNA-based spatial screening
BAR Domain Scaffolds in Dynamin-Mediated Membrane Fission