Area of research
Neurology · Physiology
Research interest
Research interests include Alpha-synuclein, Neuroscience, Dopaminergic, Parkinson's disease, Dopamine, and Disease.
Alpha-synuclein pathological deposition alters functional homeostasis and connectivity of striatal dopaminergic synapses and results in microglia activation, pathology spreading, muscle stiffness, whole brain atrophy and metabolic changes before producing frank nigral neuron deafferentation
Lewy pathology formation in patient-derived <i>GBA1</i> Parkinson’s disease midbrain organoids
DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson’s disease
Dopamine signaling modulates microglial NLRP3 inflammasome activation: implications for Parkinson’s disease
Synapsin III gene silencing redeems alpha-synuclein transgenic mice from Parkinson's disease-like phenotype
Nuclear Factor-κB Dysregulation and α-Synuclein Pathology: Critical Interplay in the Pathogenesis of Parkinson’s Disease
Extracellular clusterin limits the uptake of α‐synuclein fibrils by murine and human astrocytes
Alpha-Synuclein Preserves Mitochondrial Fusion and Function in Neuronal Cells
Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease
Synapsin III is a key component of α‐synuclein fibrils in Lewy bodies of PD brains
The End Is the Beginning: Parkinson’s Disease in the Light of Brain Imaging
Late-onset Parkinsonism in NF B/c-Rel-deficient mice