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Carel W. le Roux

University College Dublin · IE
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Area of research
Surgery · Physiology
Research interest
Research interests include Bariatric Surgery and Outcomes, Diet and metabolism studies, Diabetes Treatment and Management, and Pharmacology and Obesity Treatment.
h-index
86
citations
39,412
works
765
NIH funding
primary concept
Medicine
email

Recent publications

Definition and diagnostic criteria of clinical obesity
The Lancet Diabetes & Endocrinology 2025cited by 1,179position: middledoi
Tirzepatide as Compared with Semaglutide for the Treatment of Obesity
New England Journal of Medicine 2025cited by 374position: middledoi
Cagrilintide–Semaglutide in Adults with Overweight or Obesity and Type 2 Diabetes
New England Journal of Medicine 2025cited by 74position: middledoi
The Global Syndemic of Modifiable Cardiovascular Risk Factors Projected From 2025 to 2050
Journal of the American College of Cardiology 2025cited by 25position: middledoi
Obesity and its management in primary care setting
Journal of Diabetes and its Complications 2025cited by 8position: middledoi
Glucagon-like peptide-1 receptor agonist in myocardial infarction and atherosclerotic cardiovascular disease risk reduction: a comprehensive meta-analysis of number needed to treat, efficacy and safety
Cardiovascular Diabetology 2025cited by 8position: middledoi
Retatrutide for the treatment of obesity, obstructive sleep apnea and knee osteoarthritis: Rationale and design of the <scp>TRIUMPH</scp> registrational clinical trials
Diabetes Obesity and Metabolism 2025cited by 5position: middledoi
GLP‐1 and GIP Beyond Glycaemia: Evolutionary Roles in Energy Optimisation and Organ Protection
Diabetes/Metabolism Research and Reviews 2025cited by 0position: lastdoi
Tirzepatide for Obesity Treatment and Diabetes Prevention
New England Journal of Medicine 2024cited by 349position: middledoi
Data-driven cluster analysis identifies distinct types of metabolic dysfunction-associated steatotic liver disease
Nature Medicine 2024cited by 118position: middledoi
Cardiovascular-Liver-Metabolic Health: Recommendations in Screening, Diagnosis, and Management of Metabolic Dysfunction-Associated Steatotic Liver Disease in Cardiovascular Disease via Modified Delphi Approach
Circulation 2024cited by 102position: middledoi
Bariatric surgery for spontaneous ovulation in women living with polycystic ovary syndrome: the BAMBINI multicentre, open-label, randomised controlled trial
The Lancet 2024cited by 64position: middledoi
Efficacy and safety of tirzepatide, <scp>GLP</scp>‐1 receptor agonists, and other weight loss drugs in overweight and obesity: a network meta‐analysis
Obesity 2024cited by 57position: middledoi
Subclassification of obesity for precision prediction of cardiometabolic diseases
Nature Medicine 2024cited by 51position: middledoi
International consensus position statement on the role of obesity management medications in the context of metabolic bariatric surgery: expert guideline by the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO)
British journal of surgery 2024cited by 35position: middledoi
Resmetirom and Metabolic Dysfunction-Associated Steatohepatitis: Perspectives on Multidisciplinary Management from Global Healthcare Professionals
Current Obesity Reports 2024cited by 19position: middledoi
Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial
The Lancet 2023cited by 653position: middledoi
Trends and predictions of malnutrition and obesity in 204 countries and territories: an analysis of the Global Burden of Disease Study 2019
EClinicalMedicine 2023cited by 289position: middledoi
Lancet Diabetes &amp; Endocrinology Commission on the Definition and Diagnosis of Clinical Obesity
The Lancet Diabetes & Endocrinology 2023cited by 107position: middledoi
Tirzepatide 10 and 15 mg compared with semaglutide 2.4 mg for the treatment of obesity: An indirect treatment comparison
Diabetes Obesity and Metabolism 2023cited by 32position: firstdoi
Chronic Semaglutide Treatment in Rats Leads to Daily Excessive Concentration-Dependent Sucrose Intake
Journal of the Endocrine Society 2023cited by 16position: middledoi
Tirzepatide for the treatment of obesity: Rationale and design of the <scp>SURMOUNT</scp> clinical development program
Obesity 2022cited by 81position: firstdoi
Accurate liquid biopsy for the diagnosis of non-alcoholic steatohepatitis and liver fibrosis
Gut 2022cited by 54position: middledoi
The efficacy of <scp>GLP‐1RAs</scp> for the management of postprandial hypoglycemia following bariatric surgery: a systematic review
Obesity 2022cited by 41position: middledoi
Food Intake Following Gastric Bypass Surgery: Patients Eat Less but Do Not Eat Differently
Journal of Nutrition 2022cited by 38position: middledoi
Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis
Nature Communications 2022cited by 28position: middledoi
Obstacles and Opportunities in Managing Coexisting Obesity and CKD: Report of a Scientific Workshop Cosponsored by the National Kidney Foundation and The Obesity Society
American Journal of Kidney Diseases 2022cited by 25position: middledoi
Oromotor and somatic taste reactivity during sucrose meals reveals internal state and stimulus palatability after gastric bypass in rats
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2022cited by 3position: middledoi
Consensus Report: Definition and Interpretation of Remission in Type 2 Diabetes
Diabetes Care 2021cited by 405position: middledoi
Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial
The Lancet 2021cited by 228position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 17 papers (2013–2023)Francesco Rubino · King's College London9 papers (2012–2023) · 7 papers (2015–2023)Ruth Price · University of Ulster7 papers (2018–2022)Geltrude Mingrone · Istituto di Analisi dei Sistemi ed Informatica Antonio Ruberti6 papers (2013–2023)Georgios K. Dimitriadis · Eli Lilly (United States)5 papers (2022–2025)Alexander D. Miras · Letterkenny University Hospital5 papers (2013–2024) · 5 papers (2015–2022) · 4 papers (2018–2022)Nicholas Chew · National Heart Centre Singapore4 papers (2022–2025)Stefan R. Bornstein · Phoenix Contact (Germany)4 papers (2018–2022)Ameet G. Patel · King's College Hospital NHS Foundation Trust3 papers (2013–2022)Amy E. Rothberg · Michigan United3 papers (2021–2021)Hertzel C. Gerstein · McMaster University3 papers (2021–2021)Bryan Chong · National University of Singapore3 papers (2024–2025)Douglas Twenefour · Diabetes UK3 papers (2021–2021)Mathijs C. Bunck · Eli Lilly (United States)3 papers (2022–2024)Louis J. Aronne · Cornell University3 papers (2022–2025)Robert F. Kushner · Northwestern University3 papers (2021–2022) · 3 papers (2021–2022)
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