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John T. Poirier

NYU Langone Health · US
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Area of research
Oncology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Lung Cancer Research Studies, Lung Cancer Treatments and Mutations, Radiopharmaceutical Chemistry and Applications, and Neuroendocrine Tumor Research Advances.
h-index
58
citations
16,899
works
420
NIH funding
primary concept
Medicine
email

Recent publications

Glutamine antagonist DRP-104 suppresses tumor growth and enhances response to checkpoint blockade in <i>KEAP1</i> mutant lung cancer
Science Advances 2024cited by 57position: middledoi
Imaging with [89Zr]Zr-DFO-SC16.56 anti-DLL3 antibody in patients with high-grade neuroendocrine tumours of the lung and prostate: a phase 1/2, first-in-human trial
The Lancet Oncology 2024cited by 46position: lastdoi
A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist
PLoS Biology 2024cited by 13position: middledoi
KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance
Cell Reports 2023cited by 124position: middledoi
Clinical Benefit From Immunotherapy in Patients With SCLC Is Associated With Tumor Capacity for Antigen Presentation
Journal of Thoracic Oncology 2023cited by 84position: middledoi
Inflammation in the tumor-adjacent lung as a predictor of clinical outcome in lung adenocarcinoma
Nature Communications 2023cited by 25position: middledoi
KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition
Cancer Cell 2022cited by 94position: middledoi
Delta-like ligand 3–targeted radioimmunotherapy for neuroendocrine prostate cancer
Proceedings of the National Academy of Sciences 2022cited by 56position: middledoi
Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer
Cancer Cell 2021cited by 423position: middledoi
Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity
Cancer Cell 2021cited by 170position: middledoi
ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer
Nature Cancer 2021cited by 134position: middledoi
Replication and single-cycle delivery of SARS-CoV-2 replicons
Science 2021cited by 82position: middledoi
Rlf–Mycl Gene Fusion Drives Tumorigenesis and Metastasis in a Mouse Model of Small Cell Lung Cancer
DSpace@MIT (Massachusetts Institute of Technology) 2021cited by 43position: middle
Targeting the Atf7ip–Setdb1 Complex Augments Antitumor Immunity by Boosting Tumor Immunogenicity
Cancer Immunology Research 2021cited by 39position: middledoi
A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry
Viruses 2021cited by 20position: middledoi
Synthesis and Comparative <i>In Vivo</i> Evaluation of Site-Specifically Labeled Radioimmunoconjugates for DLL3-Targeted ImmunoPET
Bioconjugate Chemistry 2021cited by 19position: middledoi
Regenerative lineages and immune-mediated pruning in lung cancer metastasis
Nature Medicine 2020cited by 489position: middledoi
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
Cell 2020cited by 437position: lastdoi
Emergence of a High-Plasticity Cell State during Lung Cancer Evolution
Cancer Cell 2020cited by 393position: middledoi
HER2-Mediated Internalization of Cytotoxic Agents in <i>ERBB2</i> Amplified or Mutant Lung Cancers
Cancer Discovery 2020cited by 282position: middledoi
Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer
Cell Reports 2020cited by 241position: middledoi
New Approaches to SCLC Therapy: From the Laboratory to the Clinic
Journal of Thoracic Oncology 2020cited by 172position: firstdoi
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
Cell Host & Microbe 2020cited by 170position: middledoi
Lineage Reversion Drives WNT Independence in Intestinal Cancer
Cancer Discovery 2020cited by 81position: middledoi
Direct genome editing of patient-derived xenografts using CRISPR-Cas9 enables rapid in vivo functional genomics
Nature Cancer 2020cited by 52position: lastdoi
Epigenetic CRISPR Screens Identify <i>Npm1</i> as a Therapeutic Vulnerability in Non–Small Cell Lung Cancer
Cancer Research 2020cited by 30position: middledoi
Single cell profiling reveals novel tumor and myeloid subpopulations in small cell lung cancer
bioRxiv (Cold Spring Harbor Laboratory) 2020cited by 8position: middledoi
Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data
Nature reviews. Cancer 2019cited by 1,265position: middledoi
ONECUT2 is a driver of neuroendocrine prostate cancer
Nature Communications 2019cited by 241position: middledoi
Acquired BRAF Rearrangements Induce Secondary Resistance to EGFR therapy in EGFR-Mutated Lung Cancers
Journal of Thoracic Oncology 2019cited by 96position: middledoi

Grants

Research at Ultra High Energies
NSF9207138$250,0001992–1994PIRePORTER
Research at Ultra High Energies
NSF9106448$150,0001991–1993PIRePORTER
Research at Ultra High Energy Cosmic Rays and Particle Physics
NSF8814194$487,0001988–1992PIRePORTER
Research in Elementary Particle Physics
NSF8713407$90,0001987–1989PIRePORTER
Research in Elementary Particle Physics
NSF8509316$264,8691985–1987PIRePORTER
Research in Elementary Particle Physics
NSF8304238$340,0001983–1985PIRePORTER
Elementary Particle Physics
NSF8112897$320,0001981–1983PIRePORTER
Elementary Particle Physics
NSF7906103$284,4101979–1981PIRePORTER
Elementary Particle Physics
NSF7424762$183,0001974–1978PIRePORTER

Frequent collaborators

Charles M. Rudin · New York Proton Center26 papers (2015–2024)Elisa de Stanchina · European Molecular Biology Laboratory8 papers (2015–2020)Eric E. Gardner · The University of Texas MD Anderson Cancer Center5 papers (2015–2017)Benjamin H. Lok · King's College Hospital5 papers (2017–2019)Viola Allaj · Memorial Sloan Kettering Cancer Center4 papers (2017–2021)Scott W. Lowe · Memorial Sloan Kettering Cancer Center4 papers (2016–2020)Francisco J. Sánchez‐Rivera · Howard Hughes Medical Institute4 papers (2018–2021)Linde A. Miles · Cincinnati Children's Hospital Medical Center4 papers (2016–2021)Jason S. Lewis · WinnMed4 papers (2017–2022)Natasha Rekhtman · Kettering University4 papers (2017–2020)Charles M. Rice · Rockefeller University3 papers (2020–2021)Margaret R. MacDonald · Rockefeller University3 papers (2020–2021)Àlvaro Quintanal-Villalonga · Research Institute Hospital 12 de Octubre3 papers (2020–2021)Sai Kiran Sharma · National Cancer Institute3 papers (2017–2021)Afshin Dowlati · University Hospitals of Cleveland3 papers (2017–2019)Jacob Pourat · Thomas Jefferson University3 papers (2017–2021)Triparna Sen · University of British Columbia3 papers (2020–2023)William M. Schneider · Rockefeller University3 papers (2020–2021)Trudy G. Oliver · Duke University3 papers (2019–2021)J. Laird · New York University3 papers (2017–2019)
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