Area of research
Infectious Diseases · Animal Science and Zoology
Research interest
Research interests include Animal Virus Infections Studies, Viral gastroenteritis research and epidemiology, Viral Infections and Immunology Research, and SARS-CoV-2 and COVID-19 Research.
Double-membrane-spanning RNA export pores are a conserved feature in nidovirus replication organelles
A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein
A coronavirus assembly inhibitor that targets the viral membrane protein
A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein.
A coronavirus assembly inhibitor that targets the viral membrane protein.
Immune responses to SARS-CoV-2 in sub-Saharan Africa and western Europe: a retrospective, population-based, cross-sectional study.
Structural insights into MERS and SARS coronavirus membrane proteins.
CD81 is a receptor for equine arteritis virus (family: <i>Arteriviridae</i>).
Perturbation of <i>de novo</i> lipogenesis hinders MERS-CoV assembly and release, but not the biogenesis of viral replication organelles.
Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase
Deubiquitinating activity of SARS-CoV-2 papain-like protease does not influence virus replication or innate immune responses in vivo.
A Cool Look at Positive-Strand RNA Virus Replication Organelles: New Insights from Cryo-Electron Microscopy.
The Main Protease of Middle East Respiratory Syndrome Coronavirus Induces Cleavage of Mitochondrial Antiviral Signaling Protein to Antagonize the Innate Immune Response.
Characterization of SARS-CoV-2 replication in human H1299/ACE2 cells: A versatile and practical infection model for antiviral research and beyond.
Longitudinal soluble marker profiles reveal strong association between cytokine storms resulting from macrophage activation and disease severity in COVID-19 disease.
<i>Epi</i>-Cyclophellitol Cyclosulfate, a Mechanism-Based Endoplasmic Reticulum α-Glucosidase II Inhibitor, Blocks Replication of SARS-CoV-2 and Other Coronaviruses.
A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein
Prolonged fecal shedding of replication-competent virus, lasting immune activation, and intestinal inflammation in a rhesus macaque after experimental SARS-CoV-2 infection.
Perturbation of <i>de novo</i> lipogenesis hinders MERS-CoV assembly and release, but not the biogenesis of viral replication organelles
Impact of Changes in Human Airway Epithelial Cellular Composition and Differentiation on SARS-CoV-2 Infection Biology.
Host biomarker-based quantitative rapid tests for detection and treatment monitoring of tuberculosis and COVID-19.
The alphavirus nonstructural protein 2 NTPase induces a host translational shut-off through phosphorylation of eEF2 via cAMP-PKA-eEF2K signaling.
Engineering potent live attenuated coronavirus vaccines by targeted inactivation of the immune evasive viral deubiquitinase.
Honokiol Inhibits SARS-CoV-2 Replication in Cell Culture at a Post-Entry Step.
R-Propranolol Has Broad-Spectrum Anti-Coronavirus Activity and Suppresses Factors Involved in Pathogenic Angiogenesis.
Highly Potent Antisense Oligonucleotides Locked Nucleic Acid Gapmers Targeting the SARS-CoV-2 RNA Genome.
Voclosporin and the Antiviral Effect Against SARS-CoV-2 in Immunocompromised Kidney Patients.
Structures and functions of coronavirus replication-transcription complexes and their relevance for SARS-CoV-2 drug design.
Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8<sup>+</sup> T cell responses following COVID-19.
Potent Inhibition of SARS-CoV-2 nsp14 <i>N</i>7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues.