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Michael W. Konstan

The Ohio State University Wexner Medical Center ·
Area of research
Pulmonary and Respiratory Medicine · Physiology
Research interest
Research interests include Medicine, Cystic fibrosis, Internal medicine, Ivacaftor, Placebo, and Cystic fibrosis transmembrane conductance regulator.
h-index
citations
5,479
works
40
NIH funding
primary concept
email

Recent publications

Sweat chloride reflects CFTR function and correlates with clinical outcomes following CFTR modulator treatment
Journal of Cystic Fibrosis 2025cited by 21position: middledoi
Effects of the Communities that Heal (CTH) intervention on perceived opioid-related community stigma in the HEALing Communities Study: results of a multi-site, community-level, cluster-randomized trial
The Lancet Regional Health - Americas 2024cited by 15position: middledoi
Advancing the pipeline of cystic fibrosis clinical trials: a new roadmap with a global trial network perspective
The Lancet Respiratory Medicine 2023cited by 31position: middledoi
Genomic heterogeneity underlies multidrug resistance in Pseudomonas aeruginosa: A population-level analysis beyond susceptibility testing
PLoS ONE 2022cited by 22position: middledoi
Rate of Lung Function Decline in People with Cystic Fibrosis Having a Residual Function Gene Mutation
Pulmonary Therapy 2022cited by 4position: middledoi
Measuring the impact of CFTR modulation on sweat chloride in cystic fibrosis: Rationale and design of the CHEC-SC study
Journal of Cystic Fibrosis 2021cited by 22position: middledoi
Empire-CF study: A phase 2 clinical trial of leukotriene A4 hydrolase inhibitor acebilustat in adult subjects with cystic fibrosis
Journal of Cystic Fibrosis 2021cited by 19position: middledoi
The HEALing (Helping to End Addiction Long-term SM) Communities Study: Protocol for a cluster randomized trial at the community level to reduce opioid overdose deaths through implementation of an integrated set of evidence-based practices
Drug and Alcohol Dependence 2020cited by 149position: middledoi
Efficacy and safety of ataluren in patients with nonsense-mutation cystic fibrosis not receiving chronic inhaled aminoglycosides: The international, randomized, double-blind, placebo-controlled Ataluren Confirmatory Trial in Cystic Fibrosis (ACT CF)
Journal of Cystic Fibrosis 2020cited by 65position: firstdoi
Disease progression in patients with cystic fibrosis treated with ivacaftor: Data from national US and UK registries
Journal of Cystic Fibrosis 2019cited by 251position: middledoi
Amikacin liposome inhalation suspension for chronic Pseudomonas aeruginosa infection in cystic fibrosis
Journal of Cystic Fibrosis 2019cited by 53position: middledoi
Lung function changes before and after pulmonary exacerbation antimicrobial treatment in cystic fibrosis
Pediatric Pulmonology 2019cited by 27position: middledoi
Association of High-Dose Ibuprofen Use, Lung Function Decline, and Long-Term Survival in Children with Cystic Fibrosis
Annals of the American Thoracic Society 2018cited by 61position: firstdoi
Impact of CFTR Modulation on Intestinal pH, Motility, and Clinical Outcomes in Patients With Cystic Fibrosis and the G551D Mutation
Clinical and Translational Gastroenterology 2017cited by 150position: middledoi
KB001-A, a novel anti-inflammatory, found to be safe and well-tolerated in cystic fibrosis patients infected with Pseudomonas aeruginosa
Journal of Cystic Fibrosis 2017cited by 104position: middledoi
Risk factors for mortality before age 18 years in cystic fibrosis
Pediatric Pulmonology 2017cited by 95position: lastdoi
Lumacaftor/Ivacaftor Treatment of Patients with Cystic Fibrosis Heterozygous for <i>F508del-CFTR</i>
Annals of the American Thoracic Society 2017cited by 89position: middledoi
Relationship of Antibiotic Treatment to Recovery after Acute FEV1 Decline in Children with Cystic Fibrosis
Annals of the American Thoracic Society 2017cited by 42position: lastdoi
Treatment Setting and Outcomes of Cystic Fibrosis Pulmonary Exacerbations
Annals of the American Thoracic Society 2017cited by 36position: lastdoi
Lung function decline is delayed but not decreased in patients with cystic fibrosis and the R117H gene mutation
Journal of Cystic Fibrosis 2017cited by 18position: middledoi
54 Relationship between rate of percent predicted FEV1 (ppFEV1) decline and baseline and acute change in ppFEV1 in patients (pts) with cystic fibrosis (CF) treated with lumacaftor/ivacaftor (LUM/IVA)
Journal of Cystic Fibrosis 2017cited by 0position: firstdoi
Assessment of safety and efficacy of long-term treatment with combination lumacaftor and ivacaftor therapy in patients with cystic fibrosis homozygous for the F508del-CFTR mutation (PROGRESS): a phase 3, extension study
The Lancet Respiratory Medicine 2016cited by 283position: firstdoi
Efficacy and safety of lumacaftor/ivacaftor combination therapy in patients with cystic fibrosis homozygous for Phe508del CFTR by pulmonary function subgroup: a pooled analysis
The Lancet Respiratory Medicine 2016cited by 153position: middledoi
Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del<i>CFTR</i>
New England Journal of Medicine 2015cited by 1,616position: middledoi
Sustained Benefit from Ivacaftor Demonstrated by Combining Clinical Trial and Cystic Fibrosis Patient Registry Data
American Journal of Respiratory and Critical Care Medicine 2015cited by 238position: lastdoi
Forced Expiratory Volume in 1 Second Variability Helps Identify Patients with Cystic Fibrosis at Risk of Greater Loss of Lung Function
The Journal of Pediatrics 2015cited by 60position: middledoi
Behavioral and Nutritional Treatment for Preschool-Aged Children With Cystic Fibrosis
JAMA Pediatrics 2015cited by 39position: middledoi
A CFTR corrector (lumacaftor) and a CFTR potentiator (ivacaftor) for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation: a phase 2 randomised controlled trial
The Lancet Respiratory Medicine 2014cited by 441position: middledoi
Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial
The Lancet Respiratory Medicine 2014cited by 335position: middledoi
Pooled analysis of tiotropium Respimat® pharmacokinetics in cystic fibrosis
Pulmonary Pharmacology & Therapeutics 2014cited by 6position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 17 papers (2012–2022)Wayne J. Morgan · University of Illinois Chicago14 papers (2012–2022)Donald R. VanDevanter · Case Western Reserve University10 papers (2012–2021) · 10 papers (2013–2022)Nicole Mayer-Hamblett · Case Western Reserve University8 papers (2013–2025)Gregory S. Sawicki · Boston Children's Hospital8 papers (2012–2022)Jeffrey S. Wagener · University of Colorado Denver8 papers (2012–2019)Steven M. Rowe · University of Alabama at Birmingham8 papers (2013–2021)Bonnie W. Ramsey · Seattle Children's Hospital7 papers (2013–2025) · 6 papers (2015–2025)Christopher H. Goss · University of Kentucky5 papers (2013–2022) · 5 papers (2014–2017)Michael S. Schechter · Virginia Commonwealth University4 papers (2012–2017)Richard B. Moss · Palo Alto University4 papers (2016–2022)Alexandra L. Quittner · Joe DiMaggio Children's Hospital4 papers (2012–2013)J.S. Elborn · Xiamen Tungsten (China)4 papers (2014–2021)Gautham Marigowda · Berlin Institute of Health at Charité - Universitätsmedizin Berlin4 papers (2015–2017)Susanna A. McColley · Northwestern University4 papers (2014–2017)Michael Boyle · Royal College of Surgeons in Ireland4 papers (2014–2017)Xiaohong Huang · AbbVie (United States)4 papers (2014–2016)