Area of research
Materials Chemistry · Molecular Biology
Research interest
Research interests include Enzyme Structure and Function, Protein Structure and Dynamics, Mass Spectrometry Techniques and Applications, and Antibiotic Resistance in Bacteria.
Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2
Domain crossover in the reductase subunit of NADPH-dependent assimilatory sulfite reductase
Domain Swapping in the Reductase Subunit of Nadph-Dependent Assimilatory Sulfite Reductase
Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature
Neutron scattering maps the higher-order assembly of NADPH-dependent assimilatory sulfite reductase
Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication
Structural, Electronic, and Electrostatic Determinants for Inhibitor Binding to Subsites S1 and S2 in SARS-CoV-2 Main Protease
Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase.
Direct Observation of Protonation State Modulation in SARS-CoV-2 Main Protease upon Inhibitor Binding with Neutron Crystallography.
Structural plasticity of the selectivity filter in a nonselective ion channel
Small-angle neutron scattering solution structures of NADPH-dependent sulfite reductase
Small-angle neutron scattering solution structures of NADPH-dependent sulfite reductase.
Conformational Dynamics in the Interaction of SARS-CoV-2 Papain-like Protease with Human Interferon-Stimulated Gene 15 Protein.
Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography.
Substrate Binding Stiffens Aspartate Aminotransferase by Altering the Enzyme Picosecond Vibrational Dynamics.
A nucleotide-dependent oligomerization of the Escherichia coli replication initiator DnaA requires residue His136 for remodeling of the chromosomal origin.
Small-angle neutron scattering solution structures of NADPH-dependent sulfite reductase
Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex.
Pressure and Temperature Effects on the Formation of Aminoacrylate Intermediates of Tyrosine Phenol-lyase Demonstrate Reaction Dynamics
Intrinsically Disordered Protein Exhibits Both Compaction and Expansion under Macromolecular Crowding
Neutron scattering in the biological sciences: progress and prospects
Small Angle Neutron Scattering of the Intrinsically Disordered Protein FlgM under Crowded Conditions