Area of research
Neurology · Molecular Biology
Research interest
Research interests include Genetic Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis Research, Parkinson's Disease Mechanisms and Treatments, and Mitochondrial Function and Pathology.
Engineering a membrane protein chaperone to ameliorate the proteotoxicity of mutant huntingtin.
A brief guide to analyzing expression quantitative trait loci.
A comparison study of pathological features and drug efficacy between Drosophila models of C9orf72 ALS/FTD.
Monitoring lipid alterations in <i>Drosophila</i> heads in an amyotrophic lateral sclerosis model with time-of-flight secondary ion mass spectrometry.
Structural Dynamics Analysis of USP14 Activation by AKT-Mediated Phosphorylation.
Baf-mediated transcriptional regulation of teashirt is essential for the development of neural progenitor cell lineages.
Peroxiredoxin 3 deficiency induces cardiac hypertrophy and dysfunction by impaired mitochondrial quality control
Brain Endothelial Cells Utilize Glycolysis for the Maintenance of the Transcellular Permeability.
CBP-Mediated Acetylation of Importin α Mediates Calcium-Dependent Nucleocytoplasmic Transport of Selective Proteins in <i>Drosophila</i> Neurons.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>.
Disruption of nucleocytoplasmic trafficking as a cellular senescence driver.
Deubiquitinase OTUD5 is a positive regulator of mTORC1 and mTORC2 signaling pathways.
Small-Molecule Inhibitors Targeting Proteasome-Associated Deubiquitinases.
Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Phospholipid Changes in a <i>Drosophila</i> Model of Early Amyotrophic Lateral Sclerosis.
C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent nuclear accumulation of Staufen in neurons.
The Perspectives of Early Diagnosis of Schizophrenia Through the Detection of Epigenomics-Based Biomarkers in iPSC-Derived Neurons.
PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies.
Deubiquitination Reactions on the Proteasome for Proteasome Versatility.
Cytosolic calcium regulates cytoplasmic accumulation of TDP-43 through Calpain-A and Importin α3.
The Mechanisms of Nuclear Proteotoxicity in Polyglutamine Spinocerebellar Ataxias.
<i>C9orf72</i>-Associated Arginine-Rich Dipeptide Repeat Proteins Reduce the Number of Golgi Outposts and Dendritic Branches in Drosophila Neurons.
Dietary Antioxidants and the Mitochondrial Quality Control: Their Potential Roles in Parkinson's Disease Treatment.
Global transcriptional downregulation of TREX and nuclear trafficking machinery as pan-senescence phenomena: evidence from human cells and tissues.
NF-κB disinhibition contributes to dendrite defects in fly models of neurodegenerative diseases.
Discovery of new epigenomics-based biomarkers and the early diagnosis of neurodegenerative diseases.
Performance Validation of a Planar Hall Resistance Biosensor through Beta-Amyloid Biomarker.
Dysregulated Plasma Membrane Turnover Underlying Dendritic Pathology in Neurodegenerative Diseases.
Ataxin-2 Dysregulation Triggers a Compensatory Fragile X Mental Retardation Protein Decrease in <i>Drosophila</i> C4da Neurons.
Coiled-coil structure-dependent interactions between polyQ proteins and Foxo lead to dendrite pathology and behavioral defects
Activity of the mitochondrial calcium uniporter varies greatly between tissues
Identity, Networks, and The Origins of Participatory Democracy
SBIR Phase I: Low-complexity, High-throughput Wireless Networking
Development of Methodology for Design of Snow Roads and Airstrips
Research Initiation -- Finite Element Analysis of StructuresUndergoing Creep With Material Damage
Peptide Antibiotic Synthesis