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David J. Friedman

Broad Institute ·
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Area of research
Nephrology · Genetics
Research interest
Research interests include Renal Diseases and Glomerulopathies, Chronic Kidney Disease and Diabetes, Chronic Lymphocytic Leukemia Research, and Dialysis and Renal Disease Management.
h-index
49
citations
13,956
works
188
NIH funding
primary concept
email

Recent publications

Safety Assessment of a 1940 nm Tm:YAP Laser for Fractional Skin Ablation in a Swine Model
Lasers in Surgery and Medicine 2025cited by 1position: middledoi
Genetic risk factors for Mesoamerican nephropathy
Proceedings of the National Academy of Sciences 2024cited by 13position: firstdoi
Systematic Review of Kidney Injury Biomarkers for the Evaluation of CKD of Uncertain Etiology
Kidney International Reports 2024cited by 11position: middledoi
Evaluation of a Novel Ablative 1940 nm Pulsed Laser for Skin Rejuvenation
Lasers in Surgery and Medicine 2024cited by 4position: middledoi
Inaxaplin for Proteinuric Kidney Disease in Persons with Two <i>APOL1</i> Variants
New England Journal of Medicine 2023cited by 194position: middledoi
Strong protective effect of the APOL1 p.N264K variant against G2-associated focal segmental glomerulosclerosis and kidney disease
Nature Communications 2023cited by 65position: middledoi
Heat stress and heat strain among outdoor workers in El Salvador and Nicaragua
Journal of Exposure Science & Environmental Epidemiology 2023cited by 25position: middledoi
Metabolic Features of Increased Gut Permeability, Inflammation, and Altered Energy Metabolism Distinguish Agricultural Workers at Risk for Mesoamerican Nephropathy
Metabolites 2023cited by 12position: lastdoi
Urinary Metabolomic Profile of Youth at Risk of Chronic Kidney Disease in Nicaragua
Kidney360 2023cited by 9position: middledoi
High prevalence of chronic kidney disease of unknown etiology among workers in the Mesoamerican Nephropathy Occupational Study
BMC Nephrology 2022cited by 37position: middledoi
APOL1 Nephropathy: From Genetics to Clinical Applications
Clinical Journal of the American Society of Nephrology 2020cited by 260position: firstdoi
Biomarkers of kidney injury among children in a high-risk region for chronic kidney disease of uncertain etiology
Pediatric Nephrology 2020cited by 37position: middledoi
Circulating testican-2 is a podocyte-derived marker of kidney health
Proceedings of the National Academy of Sciences 2020cited by 36position: middledoi
Urinary Metals Concentrations and Biomarkers of Autoimmunity among Navajo and Nicaraguan Men
International Journal of Environmental Research and Public Health 2020cited by 18position: middledoi
Contributions of Rare Gene Variants to Familial and Sporadic FSGS
Journal of the American Society of Nephrology 2019cited by 57position: middledoi
Prevalence and Risk Factors for CKD Among Brickmaking Workers in La Paz Centro, Nicaragua
American Journal of Kidney Diseases 2019cited by 52position: middledoi
Investigating Possible Infectious Causes of Chronic Kidney Disease of Unknown Etiology in a Nicaraguan Mining Community
American Journal of Tropical Medicine and Hygiene 2019cited by 33position: middledoi
Acute Kidney Injury in Sugarcane Workers at Risk for Mesoamerican Nephropathy
American Journal of Kidney Diseases 2018cited by 100position: lastdoi
<i>UBD</i> modifies <i>APOL1</i> -induced kidney disease risk
Proceedings of the National Academy of Sciences 2018cited by 68position: middledoi
Association of Apolipoprotein L-1 polymorphisms with blood pressure in three multi-ethnic African studies
Journal of Global Health Reports 2018cited by 0position: lastdoi
Characterization of Mesoamerican Nephropathy in a Kidney Failure Hotspot in Nicaragua
American Journal of Kidney Diseases 2016cited by 56position: lastdoi
A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy
Nephrology Dialysis Transplantation 2016cited by 39position: lastdoi
APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases
Proceedings of the National Academy of Sciences 2015cited by 233position: middledoi
<i>APOL1</i> Genotype, Kidney and Cardiovascular Disease, and Death in Older Adults
Arteriosclerosis Thrombosis and Vascular Biology 2015cited by 87position: middledoi
Urine biomarkers of kidney injury among adolescents in Nicaragua, a region affected by an epidemic of chronic kidney disease of unknown aetiology
Nephrology Dialysis Transplantation 2015cited by 80position: middledoi
Innate immunity pathways regulate the nephropathy gene Apolipoprotein L1
Kidney International 2014cited by 354position: lastdoi
Evolution of the primate trypanolytic factor APOL1
Proceedings of the National Academy of Sciences 2014cited by 219position: middledoi
Carbamylation of Serum Albumin as a Risk Factor for Mortality in Patients with Kidney Failure
Science Translational Medicine 2013cited by 194position: middledoi
Increased Burden of Cardiovascular Disease in Carriers of <i>APOL1</i> Genetic Variants
Circulation Research 2013cited by 157position: middledoi
The APOL1 Genotype of African American Kidney Transplant Recipients Does Not Impact 5-Year Allograft Survival
American Journal of Transplantation 2012cited by 182position: middledoi

Grants

Host and Viral Influences on Phage Lambda Development
NSF7610561$100,0001976–1978PIRePORTER

Frequent collaborators

Martin R. Pollak · Broad Institute12 papers (2012–2023)Daniel R. Brooks · Boston University12 papers (2015–2024)Damaris López Pilarte · University of the Pacific11 papers (2015–2023)Madeleine K. Scammell · Boston University9 papers (2016–2024)Juan José Amador · Boston University9 papers (2015–2024)Oriana Ramírez‐Rubio · Barcelona Institute for Global Health8 papers (2015–2023)Michael D. McClean · VA Greater Los Angeles Healthcare System7 papers (2015–2023)Jessica H. Leibler · Boston University6 papers (2019–2023)Seth L. Alper · Massachusetts Institute of Technology5 papers (2014–2018)Rebecca L. Laws · Centers for Disease Control and Prevention5 papers (2015–2020)Giulio Genovese · Broad Institute5 papers (2012–2019)Iris Delgado · Universidad del Desarrollo4 papers (2022–2023) · 4 papers (2015–2019)Daniel E. Weiner · Tufts Medical Center3 papers (2015–2018)James S. Kaufman · VA NY Harbor Healthcare System3 papers (2015–2018)Emmanuel Jarquín · Ministerio de Desarrollo Agropecuario3 papers (2022–2024)Caryn Sennett · Boston University3 papers (2018–2020)Juan José Amador Velázquez · University of the Pacific3 papers (2020–2023)Sinead A. Keogh · Boston University3 papers (2022–2023)Ramón Gárcía-Trabanino · University of Birmingham3 papers (2022–2024)
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