Area of research
Oncology · Immunology
Research interest
Research interests include PARP inhibition in cancer therapy, interferon and immune responses, Prostate Cancer Treatment and Research, and Cancer Genomics and Diagnostics.
Single-cell chromatin accessibility reveals malignant regulatory programs in primary human cancers
FuncPEP v2.0: An Updated Database of Functional Short Peptides Translated from Non-Coding RNAs
SPOP Mutations Target STING1 Signaling in Prostate Cancer and Create Therapeutic Vulnerabilities to PARP Inhibitor–Induced Growth Suppression
Development and Validation of a Gene Signature Classifier for Consensus Molecular Subtyping of Colorectal Carcinoma in a CLIA-Certified Setting
The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells
Downregulation of 15-hydroxyprostaglandin dehydrogenase during acquired tamoxifen resistance and association with poor prognosis in ERα-positive breast cancer
The Immune Landscape of Cancer
PARP Inhibition Suppresses GR–MYCN–CDK5–RB1–E2F1 Signaling and Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer
The Immune Landscape of Cancer
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
Oncogenic Signaling Pathways in The Cancer Genome Atlas
Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer
Comprehensive Characterization of Cancer Driver Genes and Mutations
Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation
The chromatin accessibility landscape of primary human cancers
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas
Genomic and Functional Approaches to Understanding Cancer Aneuploidy
Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images
Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients
Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines
Pathogenic Germline Variants in 10,389 Adult Cancers
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma
Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas
A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers
Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer
lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer
Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas
Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics
Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers
Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas