Area of research
Infectious Diseases · Genetics
Research interest
Research interests include SARS-CoV-2 and COVID-19 Research, Viral gastroenteritis research and epidemiology, Virus-based gene therapy research, and Animal Virus Infections Studies.
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease
Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses
IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern
Ring finger protein 121 is a potent regulator of adeno-associated viral genome transcription
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies
β-<scp>d</scp>-<i>N</i>4-hydroxycytidine Inhibits SARS-CoV-2 Through Lethal Mutagenesis But Is Also Mutagenic To Mammalian Cells
Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity
SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract
SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo
The receptor-binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients
A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice
Broad neutralization of SARS-related viruses by human monoclonal antibodies
Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2
Coevolution of Adeno-associated Virus Capsid Antigenicity and Tropism through a Structure-Guided Approach
Structure-guided evolution of antigenically distinct adeno-associated virus variants for immune evasion
Adeno-associated viral vector-mediated immune responses: Understanding barriers to gene delivery
A Novel Activation Mechanism of Avian Influenza Virus H9N2 by Furin