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Scott G. Filler

University of California, Los Angeles · US
Area of research
Infectious Diseases · Epidemiology
Research interest
Research interests include Antifungal resistance and susceptibility, Fungal Infections and Studies, Peptidase Inhibition and Analysis, and Fungal and yeast genetics research.
h-index
87
citations
27,930
works
328
NIH funding
primary concept
email

Recent publications

A humanized antibody against mucormycosis targets angioinvasion and augments the host immune response
Science Translational Medicine 2025cited by 8position: middledoi
Single-cell detection of copy number changes reveals dynamic mechanisms of adaptation to antifungals in Candida albicans
Nature Microbiology 2024cited by 25position: middledoi
Aspergillus fumigatus conidial surface-associated proteome reveals factors for fungal evasion and host immunity modulation
Nature Microbiology 2024cited by 22position: middledoi
Sulfated glycosaminoglycans are host epithelial cell targets of the Candida albicans toxin candidalysin
Nature Microbiology 2024cited by 17position: lastdoi
The <i>Candida albicans</i> reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates filamentation, biofilm formation, and oral commensalism
mBio 2023cited by 35position: middledoi
Candida albicans stimulates formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection
PLoS Pathogens 2023cited by 24position: lastdoi
Control of β-glucan exposure by the endo-1,3-glucanase Eng1 in Candida albicans modulates virulence
PLoS Pathogens 2022cited by 59position: middledoi
Niclosamide-loaded nanoparticles disrupt Candida biofilms and protect mice from mucosal candidiasis
PLoS Biology 2022cited by 26position: middledoi
Aberrant type 1 immunity drives susceptibility to mucosal fungal infections
Science 2021cited by 163position: middledoi
Mucoricin is a ricin-like toxin that is critical for the pathogenesis of mucormycosis
Nature Microbiology 2021cited by 98position: middledoi
Activation of EphA2-EGFR signaling in oral epithelial cells by Candida albicans virulence factors
PLoS Pathogens 2021cited by 87position: lastdoi
Determining Aspergillus fumigatus transcription factor expression and function during invasion of the mammalian lung
PLoS Pathogens 2021cited by 49position: lastdoi
GRP78 and Integrins Play Different Roles in Host Cell Invasion during Mucormycosis
mBio 2020cited by 112position: middledoi
Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus
Antimicrobial Agents and Chemotherapy 2020cited by 80position: middledoi
Flotillin-Dependent Membrane Microdomains Are Required for Functional Phagolysosomes against Fungal Infections
Cell Reports 2020cited by 66position: middledoi
Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality
PLoS Genetics 2020cited by 51position: middledoi
CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment
Nature Immunology 2019cited by 233position: middledoi
Candidalysin Is Required for Neutrophil Recruitment and Virulence During Systemic Candida albicans Infection
The Journal of Infectious Diseases 2019cited by 102position: middledoi
AtrR Is an Essential Determinant of Azole Resistance in Aspergillus fumigatus
mBio 2019cited by 92position: middledoi
Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis
Science Advances 2019cited by 85position: middledoi
EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection
Cell Reports 2019cited by 70position: lastdoi
A Fungal Immunotherapeutic Vaccine (NDV-3A) for Treatment of Recurrent Vulvovaginal Candidiasis—A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial
Clinical Infectious Diseases 2018cited by 202position: middledoi
Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms
Microbial Cell 2018cited by 122position: middledoi
Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in <i>Candida albicans</i>
Genetics 2018cited by 106position: middledoi
Protective immunity in recurrent <i>Staphylococcus aureus</i> infection reflects localized immune signatures and macrophage-conferred memory
Proceedings of the National Academy of Sciences 2018cited by 76position: middledoi
Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus <i>Aspergillus fumigatus</i>
mBio 2018cited by 70position: middledoi
Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis
Frontiers in Immunology 2018cited by 52position: middledoi
Functional convergence of <i>gliP</i> and <i>aspf1</i> in <i>Aspergillus fumigatus</i> pathogenicity
Virulence 2018cited by 23position: lastdoi
The Case for Adopting the “Species Complex” Nomenclature for the Etiologic Agents of Cryptococcosis
mSphere 2017cited by 413position: middledoi
EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans
Nature Microbiology 2017cited by 168position: lastdoi

Grants

No grants ingested yet.

Frequent collaborators

Norma V. Solis · UCLA Medical Center23 papers (2012–2024)Ashraf S. Ibrahim · Applied DNA Sciences (United States)17 papers (2012–2025)Marc Swidergall · University of California, Los Angeles11 papers (2016–2023)John E. Edwards · UCLA Medical Center10 papers (2012–2021)Michael R. Yeaman · LAC+USC Medical Center9 papers (2012–2024)Teclegiorgis Gebremariam · University of California, Los Angeles9 papers (2013–2021)Hong Liu · UCLA Medical Center9 papers (2013–2024)Quynh T. Phan · Harbor–UCLA Medical Center8 papers (2012–2024) · 7 papers (2013–2021)Donald C. Sheppard · McGill University Health Centre6 papers (2013–2017)Abdullah Alqarihi · UCLA Medical Center6 papers (2018–2025)Aaron P. Mitchell · University of Georgia6 papers (2013–2023)Shakti Singh · University of California, Los Angeles5 papers (2018–2025) · 5 papers (2012–2018)Sondus Alkhazraji · UCLA Medical Center5 papers (2019–2025)Priya Uppuluri · University of California, Los Angeles5 papers (2018–2025)Mark J. Lee · McGill University Health Centre5 papers (2013–2016) · 5 papers (2012–2018)Fabrice N. Gravelat · McGill University Health Centre5 papers (2013–2017)Hong K. Lee · UCLA Medical Center4 papers (2013–2018)