Area of research
Molecular Biology · Pharmacology
Research interest
Research interests include Pharmacology, Chemistry, Medicine, Colitis, Oxidative stress, and Inflammation.
Protective Effects of Oxyberberine Against Hyperuricemic Nephropathy: Mechanistic Insights From In Silico, In Vitro, and In Vivo Studies
A Hepatic Oxidative Metabolite of Palmatine Ameliorates DSS-Induced Ulcerative Colitis by Regulating Macrophage Polarization Through AMPK/NF-κB Pathway
Unveiling the sweet culprit: Excessive fructose intake leading to kidney injury through hypoxanthine accumulation
Transcriptomic analyses and machine-learning methods reveal dysregulated key genes and potential pathogenesis in human osteoarthritic cartilage
Enhancing hepatoprotective action: oxyberberine amorphous solid dispersion system targeting TLR4
Mitigation of inflammatory bowel disease-related osteoporosis by oxyberberine: Insights into the RANKL/NF-κB signaling pathway
Research progress of plant medicine and Chinese herbal compounds in the treatment of rheumatoid arthritis combined with osteoporosis
Improvement effects of a novel Chinese herbal formula in imiquimod and IL-23-stimulated mouse models of psoriasis
Liuwei Dihuang Pills Enhance Osteogenic Differentiation in MC3T3-E1 Cells through the Activation of the Wnt/β-Catenin Signaling Pathway
The effects of extracellular matrix‐degrading enzymes polymorphisms on intervertebral disc degeneration
Natural Nrf2 Inhibitors: A Review of Their Potential for Cancer Treatment
Higher systemic immune-inflammation index is associated with sarcopenia in individuals aged 18–59 years: a population-based study
Network pharmacology identifies fisetin as a treatment for osteoporosis that activates the Wnt/β-catenin signaling pathway in BMSCs
J-shaped association of serum uric acid concentrations with all-cause mortality in individuals with osteoarthritis: A prospective cohort study
Global Publication Trends and Research Hotspots of the Immune Systemand Osteoporosis: A Bibliometric and Visualization Analysis from 2012 to2022
Longbie capsules reduce bone loss in the subchondral bone of rats with comorbid osteoporosis and osteoarthritis by regulating metabolite alterations
Mechanism and Experimental Verification of Luteolin for the Treatment of Osteoporosis Based on Network Pharmacology
Major Constituents From Brucea javanica and Their Pharmacological Actions
Hypouricemic and nephroprotective effects of palmatine from Cortex Phellodendri Amurensis: A uric acid modulator targeting Keap1-Nrf2/NLRP3 axis
Oxyberberine, a novel HO-1 agonist, effectively ameliorates oxidative stress and inflammatory response in LPS/D-GalN induced acute liver injury mice via coactivating erythrocyte metabolism and Nrf2 signaling pathway
In vitro and in vivo hypoglycemia effect of oxyberberine, a novel HO-1 agonist: A renewed evidence linking HO-1 to diabetes mellitus
Quercetin enhances survival and axonal regeneration of motoneurons after spinal root avulsion and reimplantation: experiments in a rat model of brachial plexus avulsion
Oxyberberine, an absorbed metabolite of berberine, possess superior hypoglycemic effect via regulating the PI3K/Akt and Nrf2 signaling pathways
Therapeutic effect of oxyberberine on obese non-alcoholic fatty liver disease rats
The anti-hepatocellular carcinoma effect of Brucea javanica oil in ascitic tumor-bearing mice: The detection of brusatol and its role
Therapeutic effect of Brucea javanica oil emulsion on experimental Crohn’s disease in rats: Involvement of TLR4/ NF-κB signaling pathway
Palmatine ameliorated murine colitis by suppressing tryptophan metabolism and regulating gut microbiota
Prophylactic efficacy of patchoulene epoxide against ethanol-induced gastric ulcer in rats: Influence on oxidative stress, inflammation and apoptosis
Self-nanoemulsfiying drug delivery system of bruceine D: a new approach for anti-ulcerative colitis
Brusatol ameliorates 2, 4, 6-trinitrobenzenesulfonic acid-induced experimental colitis in rats: Involvement of NF-κB pathway and NLRP3 inflammasome