Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Heat shock proteins research, Endoplasmic Reticulum Stress and Disease, Protein Structure and Dynamics, and Computational Drug Discovery Methods.
The role of Bag3 in cell signaling
Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity
A first order phase transition mechanism underlies protein aggregation in mammalian cells
Hsp70–Bag3 complex is a hub for proteotoxicity-induced signaling that controls protein aggregation
Cancer cell responses to Hsp70 inhibitor JG-98: Comparison with Hsp90 inhibitors and finding synergistic drug combinations
p62 /SQSTM1 coding plasmid prevents age related macular degeneration in a rat model
The Damaging Effect of Passenger Mutations on Cancer Progression
Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration
Anticancer Effects of Targeting Hsp70 in Tumor Stromal Cells
Validation of the Hsp70–Bag3 Protein–Protein Interaction as a Potential Therapeutic Target in Cancer
Targeting the hsp70 gene delays mammary tumor initiation and inhibits tumor cell metastasis
RuvbL1 and RuvbL2 enhance aggresome formation and disaggregate amyloid fibrils
Plasmid DNA-coding p62 as a bone effective anti-inflammatory/anabolic agent
Hsp70 in cancer: back to the future
Hsp70–Bag3 Interactions Regulate Cancer-Related Signaling Networks
Proteasome Failure Promotes Positioning of Lysosomes around the Aggresome via Local Block of Microtubule-Dependent Transport
Pilot study of p62 DNA vaccine in dogs with mammary tumors
Less is more: improving proteostasis by translation slow down
Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector
Heat Shock Transcription Factor Hsf1 Is Involved in Tumor Progression via Regulation of Hypoxia-Inducible Factor 1 and RNA-Binding Protein HuR
The heat shock transcription factor Hsf1 is downregulated in DNA damage–associated senescence, contributing to the maintenance of senescence phenotype
Molecular determinants of selective clearance of protein inclusions by autophagy
ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis
Polyglutamine Toxicity Is Controlled by Prion Composition and Gene Dosage in Yeast