Area of research
Hematology · Genetics
Research interest
Research interests include Hematopoietic Stem Cell Transplantation, Mesenchymal stem cell research, Acute Myeloid Leukemia Research, and Erythrocyte Function and Pathophysiology.
Platelet factor 4 regulates hematopoietic stem cell aging
Integrated Stress Response Potentiates Ponatinib-Induced Cardiotoxicity
Hematopoietic Stem Cells and Their Bone Marrow Niches
VCAM1 confers innate immune tolerance on haematopoietic and leukaemic stem cells
The amino acid sensor GCN2 controls red blood cell clearance and iron metabolism through regulation of liver macrophages
Leukemic Stem Cells: From Leukemic Niche Biology to Treatment Opportunities
MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells
Paul S. Frenette (1965–2021)
Paul S. Frenette (1965–2021)
Paul S. Frenette (1965–2021)
Haematopoietic stem cell activity and interactions with the niche
The bone marrow microenvironment at single-cell resolution
Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche
CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine
Self-renewal of a purified <i>Tie2</i> <sup>+</sup> hematopoietic stem cell population relies on mitochondrial clearance
Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion
Osterix Marks Distinct Waves of Primitive and Definitive Stromal Progenitors during Bone Marrow Development
Acute Myelogenous Leukemia-Induced Sympathetic Neuropathy Promotes Malignancy in an Altered Hematopoietic Stem Cell Niche
Arteriolar niches maintain haematopoietic stem cell quiescence
PDGFRα and CD51 mark human Nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion
Mesenchymal Stem Cell: Keystone of the Hematopoietic Stem Cell Niche and a Stepping-Stone for Regenerative Medicine
CD169+ macrophages provide a niche promoting erythropoiesis under homeostasis and stress
Endothelial Jagged-1 Is Necessary for Homeostatic and Regenerative Hematopoiesis