Area of research
Molecular Biology · Pharmacology
Research interest
Research interests include Gut microbiota and health, Pharmacogenetics and Drug Metabolism, Cancer therapeutics and mechanisms, and Cholinesterase and Neurodegenerative Diseases.
Weight loss and omega-3 supplementation modulate the microbiome in women with increased breast cancer risk.
Glucuronidation metabolomic fingerprinting to map host-microbe metabolism
Gut Microbiota Mediate the Metabolism of Colonic Prostaglandins
Microbiota and kidney disease: the road ahead
Emerging gut microbial glycoside hydrolase inhibitors.
Glucuronidation Metabolomic Fingerprinting to Map Host-Microbe Metabolism
Sex-Dependent Responses in Mice to Indomethacin-Induced Injury and Gut Microbiome-Targeted Alleviation
Commercially Purchased and In-House Bred C57BL/6 Mice with Different Gut Microbiota Exhibit Distinct Indomethacin-Induced Toxicities.
Commercially Purchased and In-House Bred C57BL/6 Mice with Different Gut Microbiota Exhibit Distinct Indomethacin-Induced Toxicities
The role of gut microbial β-glucuronidases in carcinogenesis and cancer treatment: a scoping review.
Advanced piperazine-containing inhibitors target microbial β-glucuronidases linked to gut toxicity.
Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut
Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut.
Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate.
Microbial β-glucuronidases drive human periodontal disease etiology.
Diverse but desolate landscape of gut microbial azoreductases: A rationale for idiopathic IBD drug response.
Targeting Borrelia burgdorferi HtpG with a berserker molecule, a strategy for anti-microbial development
Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract
Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract
Gut microbial β-glucuronidases regulate host luminal proteases and are depleted in irritable bowel syndrome.
Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome
Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome.
Metagenomics combined with activity-based proteomics point to gut bacterial enzymes that reactivate mycophenolate.
A structural metagenomics pipeline for examining the gut microbiome.
Multi-omic analysis of host-microbial interactions central to the gut-brain axis.
The <i>in vitro</i> metabolism and <i>in vivo</i> pharmacokinetics of the bacterial β-glucuronidase inhibitor UNC10201652.
Metagenomics Combined with Activity-Based Proteomics Point to Gut Bacterial Enzymes that Reactivate Mycophenolate
Reporting guidelines for human microbiome research: the STORMS checklist
Plant “helper” immune receptors are Ca <sup>2+</sup> -permeable nonselective cation channels
Plant "helper" immune receptors are Ca<sup>2+</sup>-permeable nonselective cation channels.