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Louise Fleming

Imperial College Healthcare NHS Trust · GB
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Area of research
Physiology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Medicine, Asthma, Sputum, Immunology, Exacerbation, and Cohort.
h-index
citations
4,169
works
32
NIH funding
primary concept
email

Recent publications

Predictors of Response to Biologics for Severe Asthma: A Systematic Review and Meta‐Analysis
Allergy 2025cited by 6position: middledoi
Patient-centred composite scores as tools for assessment of response to biological therapy for paediatric and adult severe asthma
European Respiratory Journal 2024cited by 18position: middledoi
Exhaled Volatile Organic Compounds for Asthma Control Classification in Children with Moderate to Severe Asthma: Results from the SysPharmPediA Study
American Journal of Respiratory and Critical Care Medicine 2024cited by 11position: middledoi
Key recommendations for primary care from the 2022 Global Initiative for Asthma (GINA) update
npj Primary Care Respiratory Medicine 2023cited by 328position: middledoi
Stratification of asthma by lipidomic profiling of induced sputum supernatant
Journal of Allergy and Clinical Immunology 2023cited by 29position: middledoi
Global access and patient safety in the transition to environmentally friendly respiratory inhalers: the Global Initiative for Asthma perspective
The Lancet 2023cited by 27position: middledoi
Oropharyngeal Microbiota Clusters in Children with Asthma or Wheeze Associate with Allergy, Blood Transcriptomic Immune Pathways, and Exacerbation Risk
American Journal of Respiratory and Critical Care Medicine 2023cited by 23position: middledoi
Clinical and transcriptomic features of persistent exacerbation‐prone severe asthma in U‐BIOPRED cohort
Clinical and Translational Medicine 2022cited by 21position: middledoi
Global Initiative for Asthma Strategy 2021: executive summary and rationale for key changes
European Respiratory Journal 2021cited by 536position: middledoi
Global Initiative for Asthma Strategy 2021: Executive Summary and Rationale for Key Changes
The Journal of Allergy and Clinical Immunology In Practice 2021cited by 128position: middledoi
Global Initiative for Asthma Strategy 2021. Executive Summary and Rationale for Key Changes
Archivos de Bronconeumología 2021cited by 68position: middledoi
Global Initiative for Asthma Strategy 2021
Respirology 2021cited by 50position: middledoi
Biologicals in childhood severe asthma: the European PERMEABLE survey on the<i>status quo</i>
ERJ Open Research 2021cited by 20position: middledoi
Expert meeting report: towards a joint European roadmap to address the unmet needs and priorities of paediatric asthma patients on biologic therapy
ERJ Open Research 2021cited by 8position: middledoi
eNose breath prints as a surrogate biomarker for classifying patients with asthma by atopy
Journal of Allergy and Clinical Immunology 2020cited by 36position: middledoi
Instability of sputum molecular phenotypes in U-BIOPRED severe asthma
European Respiratory Journal 2020cited by 25position: middledoi
GINA 2019: a fundamental change in asthma management
European Respiratory Journal 2019cited by 382position: middledoi
IL-17–high asthma with features of a psoriasis immunophenotype
Journal of Allergy and Clinical Immunology 2019cited by 136position: middledoi
Contribution of airway eosinophils in airway wall remodeling in asthma: Role of <i><scp>MMP</scp>‐10</i> and <i><scp>MET</scp></i>
Allergy 2019cited by 44position: middledoi
Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation
Journal of Allergy and Clinical Immunology 2018cited by 193position: middledoi
“T2-high” in severe asthma related to blood eosinophil, exhaled nitric oxide and serum periostin
European Respiratory Journal 2018cited by 137position: middledoi
Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis
European Respiratory Journal 2018cited by 91position: middledoi
Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort
PLoS ONE 2018cited by 24position: middledoi
Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome
Journal of Proteome Research 2018cited by 20position: middledoi
Pathway discovery using transcriptomic profiles in adult-onset severe asthma
Journal of Allergy and Clinical Immunology 2017cited by 121position: middledoi
Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma
European Respiratory Journal 2017cited by 51position: middledoi
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics
Journal of Allergy and Clinical Immunology 2016cited by 292position: middledoi
A Transcriptome-driven Analysis of Epithelial Brushings and Bronchial Biopsies to Define Asthma Phenotypes in U-BIOPRED
American Journal of Respiratory and Critical Care Medicine 2016cited by 210position: middledoi
Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort
European Respiratory Journal 2015cited by 559position: middledoi
The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts
European Respiratory Journal 2015cited by 230position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Aziz Sheikh · National Institute of Technology Srinagar6 papers (2019–2023) · 6 papers (2019–2023)Roland Buhl · Johannes Gutenberg University Mainz6 papers (2019–2023)Christopher E. Brightling · University of Leicester6 papers (2021–2025)Arzu Yorgancıoğlu · Medical University of Warsaw6 papers (2019–2023)Mark L Levy · University of Edinburgh6 papers (2019–2023)Leonard B. Bacharier · University of Illinois Chicago6 papers (2019–2023)Álvaro A. Cruz · Universidade Federal da Bahia6 papers (2019–2023)Jerry A. Krishnan · IIT Research Institute6 papers (2019–2023)Fanny W.S. Ko · Icahn School of Medicine at Mount Sinai6 papers (2019–2023)Louis‐Philippe Boulet · University of Cape Town6 papers (2019–2023)Eric D. Bateman · University of Cape Town6 papers (2019–2023)Guy Brusselle · University of Colorado Denver6 papers (2019–2023)Helen K. Reddel · New South Wales Department of Health6 papers (2019–2023)Jeffrey M. Drazen · Harvard University5 papers (2021–2023)J. Mark FitzGerald · Vancouver Coastal Health5 papers (2019–2021)Kian Fan Chung · Imperial College London5 papers (2015–2025)Liesbeth Duijts · Ludwig-Maximilians-Universität München5 papers (2021–2023) · 5 papers (2021–2023)Kevin Mortimer · University of Liverpool5 papers (2021–2023)
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