Area of research
Molecular Biology · Immunology and Allergy
Research interest
Research interests include Protein Kinase Regulation and GTPase Signaling, Receptor Mechanisms and Signaling, Cell Adhesion Molecules Research, and Cellular transport and secretion.
MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic (MIP-C)
A living organoid biobank of patients with Crohn’s disease reveals molecular subtypes for personalized therapeutics
Macrophage states: there's a method in the madness
Machine learning identifies signatures of macrophage reactivity and tolerance that predict disease outcomes
Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects
An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease
Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with <i>in vitro</i> antitumor activity towards non-small lung cancer
New 1,2,3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization
COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis
Identification of novel piperazine-tethered phthalazines as selective CDK1 inhibitors endowed with in vitro anticancer activity toward the pancreatic cancer
The Host-Microbiome Response to Hyperbaric Oxygen Therapy in Ulcerative Colitis Patients
Effects of iron modulation on mesenchymal stem cell-induced drug resistance in estrogen receptor-positive breast cancer
Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19
Drug repurposing screens identify chemical entities for the development of COVID-19 interventions
Parsing the Role of PPARs in Macrophage Processes
E-cigarettes compromise the gut barrier and trigger inflammation
Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease
AI-guided discovery of the invariant host response to viral pandemics
Immunosuppression of Macrophages Underlies the Cardioprotective Effects of CST (Catestatin)
2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights
Chromogranin A regulates gut permeability <i>via</i> the antagonistic actions of its proteolytic peptides
TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin
Enhanced mitochondrial fission suppresses signaling and metastasis in triple-negative breast cancer
Helicobacter pylori infection downregulates the DNA glycosylase NEIL2, resulting in increased genome damage and inflammation in gastric epithelial cells
Host engulfment pathway controls inflammation in inflammatory bowel disease
Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi
Near-Infrared Light-Activated DNA-Agonist Nanodevice for Nongenetically and Remotely Controlled Cellular Signaling and Behaviors in Live Animals
Erythrocyte sialoglycoproteins engage Siglec-9 on neutrophils to suppress activation
The Alzheimer's disease–protective CD33 splice variant mediates adaptive loss of function via diversion to an intracellular pool
GIV/Girdin activates Gαi and inhibits Gαs via the same motif