Area of research
Oncology · Cancer Research
Research interest
Research interests include Pancreatic and Hepatic Oncology Research, Cancer Genomics and Diagnostics, Lung Cancer Treatments and Mutations, and Colorectal Cancer Treatments and Studies.
Integrated Analysis of Cell-Free DNA and Novel Protein Biomarkers for Stratification and Therapy Monitoring in Stage IV Pancreatic Cancer: A Preliminary Study
BRAF <sup>Δβ3-αC</sup> in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability
Impact of the PI3K-alpha inhibitor alpelisib on everolimus resistance and somatostatin receptor expression in an orthotopic pancreatic NEC xenograft mouse model
Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors
Neoadjuvant Therapy for Resectable Pancreatic Cancer
Transitioning the Molecular Tumor Board from Proof of Concept to Clinical Routine: A German Single-Center Analysis
Longitudinal analysis of cell-free mutated KRAS and CA 19–9 predicts survival following curative resection of pancreatic cancer
Sensitivity and Resistance of Oncogenic RAS-Driven Tumors to Dual MEK and ERK Inhibition
Perioperative cell-free mutant <i>KRAS</i> dynamics in patients with pancreatic cancer
Circulating Tumor DNA Allows Early Treatment Monitoring in BRAF- and NRAS-Mutant Malignant Melanoma
Development and Clinical Validation of Discriminatory Multitarget Digital Droplet PCR Assays for the Detection of Hot Spot KRAS and NRAS Mutations in Cell-Free DNA
Identification and Validation of a Diagnostic and Prognostic Multi-Gene Biomarker Panel for Pancreatic Ductal Adenocarcinoma
Repeated SBRT for in- and out-of-field recurrences in the liver
Pancreatic cancer: Circulating Tumor Cells and Primary Tumors show Heterogeneous KRAS Mutations
Stereotactic body radiotherapy (SBRT) for locally advanced intrahepatic and extrahepatic cholangiocarcinoma
ATM mutations and E-cadherin expression define sensitivity to EGFR-targeted therapy in colorectal cancer
Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing
Implementation of a Molecular Tumor Board in Clinical Decision Making at the Medical Center University of Freiburg