Area of research
Cancer Research · Physiology
Research interest
Research interests include Biology, Cell biology, Glycolysis, Angiogenesis, Cancer research, and Endocrinology.
Architecture of the neutrophil compartment
Single-cell atlas of the human brain vasculature across development, adulthood and disease
Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes
Endothelial metabolic control of insulin sensitivity through resident macrophages
HIF1α-dependent uncoupling of glycolysis suppresses tumor cell proliferation
Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response
Shaping the brain vasculature in development and disease in the single-cell era
GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism
Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis
Exercise-induced angiogenesis is dependent on metabolically primed ATF3/4+ endothelial cells
Recurrent training rejuvenates and enhances transcriptome and methylome responses in young and older human muscle
PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase
Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization
Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity
Macrophage-derived glutamine boosts satellite cells and muscle regeneration
The effect of resistance training, detraining and retraining on muscle strength and power, myofibre size, satellite cells and myonuclei in older men
HIF1α Suppresses Tumor Cell Proliferation through Inhibition of Aspartate Biosynthesis
Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model
Differentiation but not ALS mutations in FUS rewires motor neuron metabolism
Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis
Energy metabolism in ALS: an underappreciated opportunity?
Endothelial Cell Metabolism in Health and Disease
Intake of a Ketone Ester Drink during Recovery from Exercise Promotes mTORC1 Signaling but Not Glycogen Resynthesis in Human Muscle
Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy
Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis
Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism
Premorbid obesity, but not nutrition, prevents critical illness‐induced muscle wasting and weakness
Role of Mitochondrial Complex IV in Age-Dependent Obesity
Fatty acid carbon is essential for dNTP synthesis in endothelial cells
Metabolic control of the cell cycle