Area of research
Immunology · Ophthalmology
Research interest
Research interests include Biology, Inflammasome, Retrotransposon, Macular degeneration, Retinal pigment epithelium, and Reverse transcriptase.
Cytoplasmic synthesis of endogenous <i>Alu</i> complementary DNA via reverse transcription and implications in age-related macular degeneration
<i>Alu</i> complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity
DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs
L1 drives IFN in senescent cells and promotes age-associated inflammation
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration