Area of research
Nephrology · Molecular Biology
Research interest
Research interests include Chronic Kidney Disease and Diabetes, Renal Diseases and Glomerulopathies, Receptor Mechanisms and Signaling, and Calcium signaling and nucleotide metabolism.
IFI16 is essential to linking DNA damage and ferroptosis in acute kidney injury.
MYDGF Governs Endothelial Homeostasis in Hypertension.
Ultrasound-activated piezoelectric nanostickers for neural stem cell therapy of traumatic brain injury.
Metabolic signaling of ceramides through the FPR2 receptor inhibits adipocyte thermogenesis.
A force-sensitive adhesion GPCR is required for equilibrioception.
Development of an allosteric adhesion GPCR nanobody with therapeutic potential.
The X-Age Project to construct a Chinese aging clock.
Discovery of multi-target anti-gout agents from Eurycoma longifolia Jack through phenotypic screening and structural optimization.
Reconfiguring tutor-peer roles to foster critical thinking in medical PBL assisted by tutor-managed chatGPT.
IGFBP7: A potential target for tubular lipogenesis in CKD
Wrapping stem cells with wireless electrical nanopatches for traumatic brain injury therapy.
Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.
Oxysterol Sensing Through GPR183 Triggers Endothelial Senescence in Hypertension.
Lysosomal-Associated Protein Transmembrane 5, Tubular Senescence, and Progression of CKD.
Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters.
Association of Tryptophan/Kynurenine Metabolites with Healing in Chronic Venous Leg Ulcers
Association of biofilm and microbial metrics with healing rate in older adults with chronic venous leg ulcers
HDAC9-mediated epithelial cell cycle arrest in G2/M contributes to kidney fibrosis in male mice
Systemic inflammation indicators and risk of incident arrhythmias in 478,524 individuals: evidence from the UK Biobank cohort
HDAC9-mediated epithelial cell cycle arrest in G2/M contributes to kidney fibrosis in male mice.
Systemic inflammation indicators and risk of incident arrhythmias in 478,524 individuals: evidence from the UK Biobank cohort.
Targeting RNA oxidation by ISG20-mediated degradation is a potential therapeutic strategy for acute kidney injury
GPR97 deficiency ameliorates renal interstitial fibrosis in mouse hypertensive nephropathy.
Sleep, Fatigue, and Inflammatory Biomarkers in Older Adults with Chronic Venous Leg Ulcers Receiving Intensive Outpatient Wound Care
Disease burden and long-term trends of urinary tract infections: A worldwide report
Disease burden and long-term trends of urinary tract infections: A worldwide report.
Targeting tissue-resident memory CD8<sup>+</sup> T cells in the kidney is a potential therapeutic strategy to ameliorate podocyte injury and glomerulosclerosis.
Structures of the ADGRG2–Gs complex in apo and ligand-bound forms
JAML promotes acute kidney injury mainly through a macrophage-dependent mechanism.
Structures of the ADGRG2-G<sub>s</sub> complex in apo and ligand-bound forms.