Area of research
Molecular Biology
Research interest
Research interests include RNA Research and Splicing, Single-cell and spatial transcriptomics, Genomics and Chromatin Dynamics, and RNA and protein synthesis mechanisms.
autoFISH: a modular toolbox for sequential single-molecule RNA FISH experiments.
RNA2seg: a generalist model for cell segmentation in image-based spatial transcriptomics
A Deep Learning approach for time-consistent cell cycle phase prediction from microscopy data
Homebuilt Imaging-Based Spatial Transcriptomics: Tertiary Lymphoid Structures as a Case Example.
A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
Mitotic bookmarking redundancy by nuclear receptors in pluripotent cells
Mitotic bookmarking redundancy by nuclear receptors in pluripotent cells.
A point cloud segmentation framework for image-based spatial transcriptomics.
pyHiM: a new open-source, multi-platform software package for spatial genomics based on multiplexed DNA-FISH imaging.
autoFISH - a modular toolbox for sequential smFISH experiments
A DIY guide for image-based spatial transcriptomic: TLS as a case example
Spatially Resolved Multi-Omics Single-Cell Analyses Inform Mechanisms of Immune Dysfunction in Pancreatic Cancer
An interactive murine single-cell atlas of the lung responses to radiation injury.
HT-smFISH: a cost-effective and flexible workflow for high-throughput single-molecule RNA imaging.
Excessive self-grooming, gene dysregulation and imbalance between the striosome and matrix compartments in the striatum of <i>Shank3</i> mutant mice.
A specific molecular signature in SARS-CoV-2–infected kidney biopsies
Beneficial effects of intermittent fasting in NASH and subsequent HCC development are executed by concerted PPARα and PCK1 action in hepatocytes
A point cloud segmentation framework for image-based spatial transcriptomics
MYC and MAX drive the reactivation of the genome after mitosis
FISH-quant v2: a scalable and modular tool for smFISH image analysis.
piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development.
Sensitive visualization of SARS-CoV-2 RNA with CoronaFISH.
Excessive self-grooming, gene dysregulation and imbalance between the striosome and matrix compartments in the striatum of
<i>Shank3</i>
mutant mice
A choreography of centrosomal mRNAs reveals a conserved localization mechanism involving active polysome transport.
Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages.
Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting.
Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos.
piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development
The kinesin KIF1C transports APC-dependent mRNAs to cell protrusions.
Live single-cell transcriptional dynamics via RNA labelling during the phosphate response in plants.