Area of research
Physiology · Neurology
Research interest
Research interests include Alzheimer's disease research and treatments, Barrier Structure and Function Studies, Neurological Disease Mechanisms and Treatments, and Dementia and Cognitive Impairment Research.
The blood-brain barrier as a treatment target for neurodegenerative disorders.
A Bivalent Protease-Activated Receptor-Derived Peptide Mimics Neuronal Anti-Apoptotic Activity of Activated Protein C
Sequence of decline on the NIH-toolbox cognitive battery in a predominantly Latino sample with autosomal dominant Alzheimer's disease.
Fluid biomarkers of the neurovascular unit in cerebrovascular disease and vascular cognitive disorders: A systematic review and meta-analysis.
Correction: Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
Age of onset predicted by Aβ profiling in a novel PSEN1 (I180F) mutation.
Retraction Note: Pericyte loss influences Alzheimer-like neurodegeneration in mice.
Author Correction: Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.
Decreased functional connectivity is associated with increased levels of Cerebral Spinal Fluid soluble-PDGFRβ, a marker of blood brain barrier breakdown, in older adults.
Erratum: Zhong et al., "Protein S Protects Neurons from Excitotoxic Injury by Activating the TAM Receptor Tyro3-Phosphatidylinositol 3-Kinase-Akt Pathway through Its Sex Hormone-Binding Globulin-Like Region".
Retraction Note: Pericyte degeneration causes white matter dysfunction in the mouse central nervous system.
Molecular biomarkers for vascular cognitive impairment and dementia
Molecular biomarkers for vascular cognitive impairment and dementia.
Placental growth factor as a sensitive biomarker for vascular cognitive impairment
Placental growth factor as a sensitive biomarker for vascular cognitive impairment.
Molecular signature and functional properties of human pluripotent stem cell-derived brain pericytes
Retinotopic degeneration of the retina and optic tracts in autosomal dominant Alzheimer's disease.
Characterization of spastic paraplegia in a family with a novel <i>PSEN1</i> mutation.
Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging.
Author Correction: Apolipoprotein E controls cerebrovascular integrity via cyclophilin A.
Author Correction: Pericyte loss influences Alzheimer-like neurodegeneration in mice.
Correction: Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier.
A "multi-omics" analysis of blood-brain barrier and synaptic dysfunction in APOE4 mice.
Brain barriers and their potential role in migraine pathophysiology.
Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C.
APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer’s mice via cyclophilin A independently of amyloid-β
Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A
MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols
MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols.
Early neuroinflammation is associated with lower amyloid and tau levels in cognitively normal older adults.