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Amy S. Gladfelter

University of North Carolina at Chapel Hill · US
Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Fungal and yeast genetics research, RNA Research and Splicing, RNA and protein synthesis mechanisms, and RNA modifications and cancer.
h-index
52
citations
9,784
works
241
NIH funding
primary concept
email

Recent publications

Current practices in the study of biomolecular condensates: a community comment
Nature Communications 2025cited by 48position: middledoi
HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells
Science 2021cited by 366position: middledoi
RNA contributions to the form and function of biomolecular condensates
Nature Reviews Molecular Cell Biology 2020cited by 674position: lastdoi
The hierarchical assembly of septins revealed by high-speed AFM
Nature Communications 2020cited by 61position: middledoi
Shed Light in the DaRk LineagES of the Fungal Tree of Life—STRES
Life 2020cited by 58position: middledoi
Modeling the Mechanisms by Which Coexisting Biomolecular RNA–Protein Condensates Form
Bulletin of Mathematical Biology 2020cited by 15position: middledoi
Mathematically Modeling Mechanisms of Molecular Identity in Biomolecular Condensates
Biophysical Journal 2020cited by 1position: middledoi
Fungi in the Marine Environment: Open Questions and Unsolved Problems
mBio 2019cited by 327position: lastdoi
Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors
Neuron 2019cited by 80position: middledoi
mRNA structure determines specificity of a polyQ-driven phase separation
Science 2018cited by 544position: lastdoi
Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton
The Journal of Cell Biology 2016cited by 237position: lastdoi
Dissection of molecular assembly dynamics by tracking orientation and position of single molecules in live cells
Proceedings of the National Academy of Sciences 2016cited by 109position: middledoi
Cytoskeletal dynamics: A view from the membrane
The Journal of Cell Biology 2015cited by 193position: middledoi
MultiFocus Polarization Microscope (MF-PolScope) for 3D polarization imaging of up to 25 focal planes simultaneously
Optics Express 2015cited by 98position: middledoi
Life as a moving fluid: fate of cytoplasmic macromolecules in dynamic fungal syncytia
Current Opinion in Microbiology 2015cited by 35position: lastdoi
Quantitative spatial analysis of transcripts in multinucleate cells using single-molecule FISH
Methods 2015cited by 23position: lastdoi

Grants

Collaborative Research: Multiscale Mechanics of Septin Assembly and Curvature Sensing
NSF2438870$419,1682025–2029PIRePORTER
Evolution of the Biophysical Properties of the Septin Cytoskeleton
NSF2401042$595,1962023–2025PIRePORTER
Evolution of the Biophysical Properties of the Septin Cytoskeleton
NSF2016022$1,052,4002020–2024PIRePORTER
RoL-FELS:RAISE: Specialization and decision making among synctial nuclei
NSF1840273$1,000,0002018–2023PIRePORTER
Septin assembly and membrane organization
NSF1615138$943,1522016–2021PIRePORTER
2016 Cellular & Molecular Fungal Biology GRC, Plymouth, New Hampshire, June 19-24, 2016
NSF1607069$15,0002016–2017PIRePORTER
Mechanisms of Septin Assembly and Dynamics
NSF1212400$673,1562012–2017PIRePORTER
Septin Organization in Multinucleated Cells
NSF0719126$669,0052007–2012PIRePORTER
Starter Grant: Spatial Control of Mitosis by Septins
NSF0625814$50,0002006–2007PIRePORTER
Postdoctoral Research Fellowship in Microbial Biology for FY 2003
NSF0301028$150,0002003–2006PIRePORTER

Frequent collaborators

Jay Newby · University of Alberta3 papers (2020–2021)Kelsey Gasior · North Carolina State University3 papers (2020–2021)ChangHwan Lee · Albany State University2 papers (2015–2015) · 2 papers (2015–2016)Rudolf Oldenbourg · Brown University2 papers (2015–2016)Shalin B. Mehta · Bell (Canada)2 papers (2015–2016)Molly McQuilken · Dartmouth College2 papers (2015–2016)Patricia Occhipinti · Dartmouth College2 papers (2016–2016)Magdalena Bezanilla · Dartmouth College1 papers (2015–2015)Joseph G. Gleeson · Children’s Institute1 papers (2019–2019) · 1 papers (2019–2019)Zhiheng Xu · Guangzhou University of Chinese Medicine1 papers (2019–2019)Anne Gregor · University of Bern1 papers (2019–2019)Christina M. Termini · Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa1 papers (2018–2018)Shuibing Chen · Cornell University1 papers (2019–2019)Henrik Molina · Rockefeller University1 papers (2019–2019)Ling Yuan · The First Affiliated Hospital, Sun Yat-sen University1 papers (2019–2019) · 1 papers (2019–2019)John R. Yates · University of Montana1 papers (2021–2021)Oded Yarden · Hebrew University of Jerusalem1 papers (2019–2019)