Area of research
Molecular Biology · Hematology
Research interest
Research interests include RNA Research and Splicing, RNA modifications and cancer, Acute Myeloid Leukemia Research, and Acute Lymphoblastic Leukemia research.
HNRNPC and m6A RNA methylation control oncogenic transcription and metabolism in T-cell leukemia
Underlying biology, challenges and emergent concepts in the treatment of relapsed and refractory pediatric T-cell acute lymphoblastic leukemia
T cell acute lymphoblastic leukemia exploits a neural proinflammatory pathway to colonize the meninges
Chromatin reprogramming and bone regeneration in vitro and in vivo via the microtopography-induced constriction of cell nuclei
CXCR3/CXCL10 Signaling Pathway Drives T-ALL into the CNS/Meningeal Microenvironment
SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia
Splicing dysregulation in human hematologic malignancies: beyond splicing mutations
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia
LKB1/ <i>STK11</i> Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms
Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia
Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation
Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia
Cardiac myocyte KLF5 regulates body weight via alteration of cardiac FGF21
Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries
USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia
HiC-bench: comprehensive and reproducible Hi-C data analysis designed for parameter exploration and benchmarking
Deregulation of DUX4 and ERG in acute lymphoblastic leukemia
Emerging concepts of epigenetic dysregulation in hematological malignancies
Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a
Cardiac Myocyte KLF5 Regulates <i>Ppara</i> Expression and Cardiac Function
Genome-wide Mapping and Characterization of Notch-Regulated Long Noncoding RNAs in Acute Leukemia
From Fly Wings to Targeted Cancer Therapies: A Centennial for Notch Signaling
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
Control of Embryonic Stem Cell Identity by BRD4-Dependent Transcriptional Elongation of Super-Enhancer-Associated Pluripotency Genes
The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability
Notch pathway activation targets AML-initiating cell homeostasis and differentiation
Higher-Order Looping and Nuclear Organization of Tcra Facilitate Targeted RAG Cleavage and Regulated Rearrangement in Recombination Centers
The RAG2 C-terminus and ATM protect genome integrity by controlling antigen receptor gene cleavage
Mechanisms of Epigenetic Regulation of Leukemia Onset and Progression
A new player SETs in myeloid malignancy