Area of research
Genetics · Cancer Research
Research interest
Research interests include Estrogen and related hormone effects, Cancer, Lipids, and Metabolism, Cholesterol and Lipid Metabolism, and SARS-CoV-2 and COVID-19 Research.
Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells.
Threonyl-tRNA synthetase activates STAT3 by a nontranslational mechanism.
Cholesterol efflux protein, ABCA1, supports anticancer functions of myeloid immune cells.
Loss of Mast cells and histaminergic signaling link diet to platelet-mediated NETosis and mammary cancer recurrence
Reciprocal macrophage-MSC crosstalk drives immunomodulatory and regenerative phenotypes in a mineralized collagen scaffold
CASM potentiates STING-driven NFκB signaling in immune cells
Mineralized collagen scaffold pore architecture and glycosaminoglycan content biases anti-inflammatory macrophage phenotype
Cholesterol-targeting Wnt–β-catenin signaling inhibitors for colorectal cancer
Cholesterol-targeting Wnt-β-catenin signaling inhibitors for colorectal cancer.
Nanomedicine targeting PPAR in adipose tissue macrophages improves lipid metabolism and obesity-induced metabolic dysfunction
A necrosis inducer promotes an immunogenic response and destroys ovarian cancers in mouse xenografts and patient ascites organoids
Role of Protein Regulators of Cholesterol Homeostasis in Immune Modulation and Cancer Pathophysiology.
Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells
Co-targeting of metabolism using dietary and pharmacologic approaches reduces breast cancer metastatic burden.
Cholesterol efflux protein, ABCA1, supports anti-cancer functions of myeloid immune cells
ACSS2-Mediated Metabolic-Epigenetic Crosstalk Drives Fulvestrant Resistance and Represents a Novel Therapeutic Target
LRH-1 is a novel regulator of neutrophil-driven immune responses within the tumor microenvironment
Supplementary Data from Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy–Induced Necrosis
Supplementary Data from Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy–Induced Necrosis
Data from Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy–Induced Necrosis
Supplementary Data from Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy–Induced Necrosis
Supplementary Data from Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy–Induced Necrosis
Supplementary Data from Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy–Induced Necrosis
Gut microbiome responds to alteration in female sex hormone status and exacerbates metabolic dysfunction.
Development of NR0B2 as a therapeutic target for the re-education of tumor associated myeloid cells
Development of NR0B2 as a therapeutic target for the re-education of tumor associated myeloid cells.
27-Hydroxycholesterol Enhances Secretion of Extracellular Vesicles by ROS-Induced Dysregulation of Lysosomes.
NR0B2 re-educates myeloid immune cells to reduce regulatory T cell expansion and progression of breast and other solid tumors
NR0B2 re-educates myeloid immune cells to reduce regulatory T cell expansion and progression of breast and other solid tumors
Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells