N.N. Alexandrov National Cancer Centre ·
Area of research
Genetics · Molecular Biology
Research interest
Research interests include BRCA gene mutations in cancer, Genetic Associations and Epidemiology, DNA Repair Mechanisms, and Genetic factors in colorectal cancer.
Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification
Large-scale meta-analysis and precision functional assays identify FANCM regions in which PTVs confer different risks for ER-negative and triple-negative breast cancer
Understanding the genetic complexity of puberty timing across the allele frequency spectrum
Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions
Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction
Differences in polygenic score distributions in European ancestry populations: implications for breast cancer risk prediction
Co-observation of germline pathogenic variants in breast cancer predisposition genes: Results from analysis of the BRIDGES sequencing dataset
Publisher Correction: Understanding the genetic complexity of puberty timing across the allele frequency spectrum
Large-scale genome-wide association study of 398,238 women unveils seven novel loci associated with high-grade serous epithelial ovarian cancer risk
Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification
Analysis of variants in untranslated and promoter regions and breast cancer risk using whole genome sequencing data
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry
FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women
Evaluation of European-based polygenic risk score for breast cancer in Ashkenazi Jewish women in Israel
Understanding the genetic complexity of puberty timing across the allele frequency spectrum
Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases
Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes
Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study
Polygenic risk modeling for prediction of epithelial ovarian cancer risk
Breast cancer risks associated with missense variants in breast cancer susceptibility genes
Individual radiosensitivity reflected by γ-H2AX and 53BP1 foci predicts outcome in PSMA-targeted radioligand therapy
Rare germline copy number variants (CNVs) and breast cancer risk
Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci
Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk
Mendelian randomisation study of smoking exposure in relation to breast cancer risk
Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element
Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?
CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers
Breast cancer risks associated with missense variants in breast cancer susceptibility genes
Rare copy number variants (CNVs) and breast cancer risk