Area of research
Hematology · Genetics
Research interest
Research interests include Blood Coagulation and Thrombosis Mechanisms, Hemophilia Treatment and Research, Coagulation, Bradykinin, Polyphosphates, and Angioedema, and Platelet Disorders and Treatments.
Recurrent venous thromboembolism: association with thrombin generation and d-dimer.
Risk of First Venous Thrombosis by Comparing Different Thrombin Generation Assay Conditions: Results from the MEGA Case-control Study.
Calcium binding by γ-carboxyglutamic acid: it takes two to tether.
Citrullination of tissue factor pathway inhibitor alpha by peptidylarginine deiminase 4 impairs its natural anticoagulant activity toward factors Xa and VIIa/tissue factor and reduces binding to its cofactor protein S.
Chemokine-Binding All-D-CLIPS Peptides Identified Using Mirror-Image Phage Display.
Chemokine-binding all-D-CLIPS™ peptides identified using mirror-image phage display
CCL18 aggravates atherosclerosis by inducing CCR6-dependent T-cell influx and polarization.
In vitro and ex vivo rescue of a nonsense mutation responsible for severe coagulation factor V deficiency.
Differences in Cardiac Troponin T Composition in Myocardial Infarction and End-Stage Renal Disease Patients: A Blood Tube Effect?
Minimally modified human blood coagulation factor X to bypass direct factor Xa inhibitors.
Tissue Factor Pathway Inhibitor Modulates Endothelial and Vascular Smooth Muscle Cell Functions By Drifting Cellular Phenotypes
Why Current Detection of Vascular Calcification Falls Short and How to Improve on It.
Thiol-ene conjugation of VEGF peptide to electrospun scaffolds as potential application for angiogenesis.
Vitamin K and Hallmarks of Ageing: Focus on Diet and Gut Microbiome.
Protein arginine deiminase 4 inactivates tissue factor pathway inhibitor-alpha by enzymatic modification of functional arginine residues.
In vitro and ex vivo rescue of a nonsense mutation responsible for severe coagulation factor V deficiency
Application of the mineral-binding protein fetuin-A for the detection of calcified lesions.
Novel Amphibian Bowman-Birk-Like Inhibitor with Antioxidant and Anticoagulant Effects Ameliorates Pancreatitis Symptoms in Mice.
Sensitive Measurement of Clinically Relevant Factor VIII Levels in Thrombin Generation Assays Requires Presence of Factor XIa.
Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy.
Targeting platelet-derived CXCL12 impedes arterial thrombosis
Targeting platelet-derived CXCL12 impedes arterial thrombosis.
Differential Effects of Platelet Factor 4 (CXCL4) and Its Non-Allelic Variant (CXCL4L1) on Cultured Human Vascular Smooth Muscle Cells.
Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear
Desymmetrization via Activated Esters Enables Rapid Synthesis of Multifunctional Benzene-1,3,5-tricarboxamides and Creation of Supramolecular Hydrogelators.
Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear.
Thrombin in complex with dabigatran can still interact with PAR-1 via exosite-I and instigate loss of vascular integrity.
Dysbiosis in Patients with Chronic Kidney Disease: Let Us Talk About Vitamin K.
Molecular Detection of Venous Thrombosis in Mouse Models Using SPECT/CT.
Serial thrombin generation and exploration of alternative anticoagulants in critically ill COVID-19 patients: Observations from Maastricht Intensive Care COVID Cohort.