Area of research
Physiology · Pathology and Forensic Medicine
Research interest
Research interests include Nitric Oxide and Endothelin Effects, Cardiac Ischemia and Reperfusion, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, and Mitochondrial Function and Pathology.
Pharmacological inhibition of glycolysis at the pyruvate-to-lactate conversion stage mitigates reperfusion injury without aggravating ischemic injury in mouse hearts.
Balancing Efficacy and Safety: Discovery and Biological Activity Evaluation of Novel Nitrogen-Containing Fused Heterocyclic Cyclooxygenase Inhibitors.
CARD11-BCL10-MALT1 Complex-Dependent MALT1 Activation Facilitates Myocardial Oxidative Stress in Doxorubicin-Treated Mice via Enhancing k48-Linked Ubiquitination of Nrf2.
A Biomimetic Multifunctional Nanoplatform with Precise Targeting-Penetration and Efficient Synergistic Therapy for Ischemic Stroke.
The Chinese Herbal Medicine Li Qi Huo Xue Di Wan Ameliorates Ischemia or Hypoxia-Induced Cardiac Injury and Remodeling in the Heart Through a Mechanism Involving Reduction of Necroptosis.
Cerdulatinib Improves Sensorimotor Function and Memory Ability in Mice Suffering from Ischemic Stroke through Targeting Caspase-3-Dependent Apoptosis.
Sonic hedgehog signaling facilitates pyroptosis in mouse heart following ischemia/reperfusion via enhancing the formation of CARD10-BCL10-MALT1 complex.
Micafungin protects mouse heart against doxorubicin-induced oxidative injury via suppressing MALT1-dependent k48-linked ubiquitination of Nrf2.
Restoration of metal homeostasis: a potential strategy against neurodegenerative diseases.
The Weakened Interaction Between HECTD4 and GluN2B in Ischemic Stroke Promotes Calcium Overload and Brain Injury Through a Mechanism Involving the Decrease of GluN2B and MALT1 Ubiquitination.
Telaprevir Improves Memory and Cognition in Mice Suffering Ischemic Stroke via Targeting MALT1-Mediated Calcium Overload and Necroptosis.
Caspofungin Suppresses Brain Cell Necroptosis in Ischemic Stroke Rats via Up-Regulation of Pellino3.
DL-3-n-butylphthalide improves the endothelium-dependent vasodilation in high-fat diet-fed ApoE<sup>-/-</sup> mice via suppressing inflammation, endothelial necroptosis and apoptosis.
COVID-19-induced neurological symptoms: focus on the role of metal ions.
Role of sonic hedgehog signaling pathway in the regulation of ion channels: focus on its association with cardio-cerebrovascular diseases.
Ferroptosis occurs in phase of reperfusion but not ischemia in rat heart following ischemia or ischemia/reperfusion.
Intravenous versus Volatile Anesthetic Effects on Postoperative Cognition in Elderly Patients Undergoing Laparoscopic Abdominal Surgery
Targeting the pathways of regulated necrosis: a potential strategy for alleviation of cardio-cerebrovascular injury.
Caspofungin suppresses brain cell necroptosis in the ischemic stroke rat via up-regulation of Pellino3
Inhibition of Phosphoglycerate Mutase 5 Reduces Necroptosis in Rat Hearts Following Ischemia/Reperfusion Through Suppression of Dynamin-Related Protein 1.
Natural compound methyl protodioscin protects rat brain from ischemia/reperfusion injury through regulation of Mul1/SOD2 pathway.
Both JNK and P38 MAPK pathways participate in the protection by dexmedetomidine against isoflurane-induced neuroapoptosis in the hippocampus of neonatal rats
Dantrolene ameliorates cognitive decline and neuropathology in Alzheimer triple transgenic mice