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Richard A. Lewis

Novartis (Switzerland) · CH
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Area of research
Materials Chemistry · Computational Theory and Mathematics
Research interest
Research interests include Computational Drug Discovery Methods, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, and Chemical Synthesis and Analysis.
h-index
47
citations
8,420
works
204
NIH funding
primary concept
email

Recent publications

The Need for Continuing Blinded Pose- and Activity Prediction Benchmarks
Journal of Chemical Information and Modeling 2025cited by 11position: middledoi
GREGoR: accelerating genomics for rare diseases
Nature 2025cited by 11position: middledoi
Artificial intelligence in chemistry and drug design
Journal of Computer-Aided Molecular Design 2020cited by 162position: middledoi
D3R grand challenge 4: blind prediction of protein–ligand poses, affinity rankings, and relative binding free energies
Journal of Computer-Aided Molecular Design 2020cited by 144position: middledoi
Consensus recommendations for the use of retinoids in ichthyosis and other disorders of cornification in children and adolescents
Pediatric Dermatology 2020cited by 73position: middledoi
Clinical sites of the Undiagnosed Diseases Network: unique contributions to genomic medicine and science
Genetics in Medicine 2020cited by 42position: middledoi
Nr2f1 heterozygous knockout mice recapitulate neurological phenotypes of Bosch-Boonstra-Schaaf optic atrophy syndrome and show impaired hippocampal synaptic plasticity
Human Molecular Genetics 2019cited by 17position: middledoi
A Schlemm Canal Microstent for Intraocular Pressure Reduction in Primary Open-Angle Glaucoma and Cataract
Ophthalmology 2018cited by 220position: middledoi
Heterozygous Truncating Variants in POMP Escape Nonsense-Mediated Decay and Cause a Unique Immune Dysregulatory Syndrome
The American Journal of Human Genetics 2018cited by 164position: middledoi
ESCMID generic competencies in antimicrobial prescribing and stewardship: towards a European consensus
Clinical Microbiology and Infection 2018cited by 68position: middledoi
Lessons learned from additional research analyses of unsolved clinical exome cases
Genome Medicine 2017cited by 233position: middledoi
Clinically severe CACNA1A alleles affect synaptic function and neurodegeneration differentially
PLoS Genetics 2017cited by 90position: middledoi
Recurrent De Novo and Biallelic Variation of ATAD3A , Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes
The American Journal of Human Genetics 2016cited by 189position: middledoi
NR2F1 Mutations Cause Optic Atrophy with Intellectual Disability
The American Journal of Human Genetics 2014cited by 143position: middledoi
A Dominant Mutation in Hexokinase 1 (<i>HK1</i>) Causes Retinitis Pigmentosa
Investigative Ophthalmology & Visual Science 2014cited by 71position: middledoi
Mutations in the X-Linked Retinitis Pigmentosa Genes<i>RPGR</i>and<i>RP2</i>Found in 8.5% of Families with a Provisional Diagnosis of Autosomal Dominant Retinitis Pigmentosa
Investigative Ophthalmology & Visual Science 2013cited by 124position: middledoi
Whole-exome resequencing distinguishes cystic kidney diseases from phenocopies in renal ciliopathies
Kidney International 2013cited by 73position: middledoi
Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling
Cell 2012cited by 391position: middledoi
Mutations in<i>RPGR</i>and<i>RP2</i>Account for 15% of Males with Simplex Retinal Degenerative Disease
Investigative Ophthalmology & Visual Science 2012cited by 126position: middledoi

Grants

NSF-SSRC: Reducing Vaccine Hesitancy Through Interactive Decision Aids
NSF2241963$499,0892023–2026PIRePORTER
Language Processing as Boundedly Optimal Control of Memory, Perception, and Action
NSF1152819$401,2672012–2016PIRePORTER
RUI: Establishment of a high-density event-related potential laboratory at an undergraduate college for the study of cognitive neuroscience
NSF0116836$134,5572001–2004PIRePORTER
Laboratory Equipment to Improve Undergraduate Instruction inPhysiological Psychology
NSF8750744$6,2051987–1989PIRePORTER
Interdisciplinary Physical Assessment Laboratory
NSF7913598$3,2541979–1982PIRePORTER

Frequent collaborators

Huda Y. Zoghbi · Howard Hughes Medical Institute2 papers (2014–2019)Christian P. Schaaf · Heidelberg University2 papers (2014–2019)Stephen P. Daiger · The University of Texas Health Science Center at Houston2 papers (2013–2014)Michael K. Gilson · University of California San Diego2 papers (2020–2025)David G. Birch · Southwestern Medical Center2 papers (2013–2014)Sara J. Bowne · The University of Texas Health Science Center at Houston2 papers (2013–2014)W. Patrick Walters · Center for Cancer Research2 papers (2020–2025)Lori S. Sullivan · The University of Texas Health Science Center at Houston2 papers (2013–2014)James R. Lupski · The University of Texas Southwestern Medical Center2 papers (2014–2017)Chun‐An Chen · National Taiwan University Hospital2 papers (2014–2019)Mafei Xu · Anhui Medical University1 papers (2014–2014)Rolph Pfundt · Oxford University Hospitals NHS Trust1 papers (2014–2014)Klaas J. Wierenga · University of Oklahoma Health Sciences Center1 papers (2017–2017)Michelle L. Seymour · Baylor College of Medicine1 papers (2019–2019)Matthew Pastore · The Ohio State University1 papers (2017–2017)Elizabeth Cadena · The University of Texas Health Science Center at Houston1 papers (2014–2014)Amy S. Paller · Northwestern University1 papers (2020–2020)Daniel Reker · Massachusetts Institute of Technology1 papers (2020–2020)Daniëlle G.M. Bosch · Erasmus MC1 papers (2014–2014)Cheryl E. Avery · The University of Texas Health Science Center at Houston1 papers (2014–2014)
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