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Hui Shen

Van Andel Institute · CN
Area of research
Oncology · Surgery
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Bladder and Urothelial Cancer Treatments, Cancer Genomics and Diagnostics, and Epigenetics and DNA Methylation.
h-index
95
citations
113,848
works
458
NIH funding
primary concept
Medicine
email

Recent publications

The Somatic Mosaicism across Human Tissues Network
Nature 2025cited by 39position: middledoi
BISCUIT: an efficient, standards-compliant tool suite for simultaneous genetic and epigenetic inference in bulk and single-cell studies
Nucleic Acids Research 2024cited by 44position: lastdoi
Immunological and molecular features of the tumor microenvironment of long-term survivors of ovarian cancer
Journal of Clinical Investigation 2024cited by 17position: middledoi
Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin
Cancer Cell 2023cited by 100position: middledoi
Additional file 1 of LncRNA ANRIL promotes HR repair through regulating PARP1 expression by sponging miR-7-5p in lung cancer
Open MIND 2023cited by 0position: middledoi
Additional file 2 of LncRNA ANRIL promotes HR repair through regulating PARP1 expression by sponging miR-7-5p in lung cancer
Figshare 2023cited by 0position: middledoi
Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis
Nature Cancer 2022cited by 112position: middledoi
Copper transporter gene ATP7A: A predictive biomarker for immunotherapy and targeted therapy in hepatocellular carcinoma
International Immunopharmacology 2022cited by 14position: middledoi
Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway
Cell Reports 2021cited by 32position: middledoi
Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer
Cancer Cell 2020cited by 324position: middledoi
Menopausal hormone therapy prior to the diagnosis of ovarian cancer is associated with improved survival
Gynecologic Oncology 2020cited by 28position: middledoi
Before and After: Comparison of Legacy and Harmonized TCGA Genomic Data Commons’ Data
Cell Systems 2019cited by 199position: middledoi
Clinical lipidomics in understanding of lung cancer: Opportunity and challenge
Cancer Letters 2019cited by 76position: middledoi
The Immune Landscape of Cancer
Immunity 2018cited by 6,153position: middledoi
The chromatin accessibility landscape of primary human cancers
Science 2018cited by 1,316position: middledoi
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma
Cell Reports 2018cited by 800position: middledoi
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma
Cell Reports 2018cited by 775position: middledoi
A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers
Cancer Cell 2018cited by 697position: middledoi
Integrated Molecular Characterization of Testicular Germ Cell Tumors
Cell Reports 2018cited by 456position: firstdoi
DNA methylation loss in late-replicating domains is linked to mitotic cell division
Nature Genetics 2018cited by 450position: middledoi
Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas
Cell Reports 2018cited by 365position: middledoi
A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer
Nature Genetics 2017cited by 546position: middledoi
Integrated Molecular Characterization of Uterine Carcinosarcoma
Cancer Cell 2017cited by 441position: middledoi
The genomic landscape of tuberous sclerosis complex
Nature Communications 2017cited by 236position: middledoi
Comprehensive analyses of tumor immunity: implications for cancer immunotherapy
Genome biology 2016cited by 2,760position: middledoi
Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA
Molecular Cell 2016cited by 319position: middledoi
Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer
Cell 2015cited by 1,947position: middledoi
Comprehensive molecular characterization of gastric adenocarcinoma
Nature 2014cited by 6,465position: middledoi
Multiplatform Analysis of 12 Cancer Types Reveals Molecular Classification within and across Tissues of Origin
Cell 2014cited by 1,566position: middledoi
The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma
Cancer Cell 2014cited by 852position: middledoi

Grants

I-Corps: Biosensor for landmine detection
NSF2322309$50,0002023–2024PIRePORTER
RUI: Transcriptional Regulation of INO1 in Yeast
NSF0919218$276,4802009–2013PIRePORTER

Frequent collaborators

Peter W. Laird · Van Andel Institute7 papers (2012–2024)Scott L. Carter · Toyota Motor Corporation (Switzerland)3 papers (2012–2013)Gad Getz · Broad Institute3 papers (2012–2013)Wanding Zhou · Translational Therapeutics (United States)3 papers (2017–2024)Travis Zack · City College of San Francisco2 papers (2012–2013)Xuguang Hu · Guangzhou University of Chinese Medicine2 papers (2023–2023)Andrew D. Cherniack · Harvard University2 papers (2013–2017)Benjamin P. Berman · Henderson Community College2 papers (2018–2024)Douglas A. Levine · Merck & Co., Inc., Rahway, NJ, USA (United States)2 papers (2012–2013)Nanxi Yu · Wenzhou Medical University2 papers (2023–2023)Daniel J. Weisenberger · University of California, Los Angeles2 papers (2017–2018)Rameen Beroukhim · Broad Institute2 papers (2012–2013)Matthew Meyerson · Harvard University2 papers (2012–2013)Lei Liu · Washington University in St. Louis2 papers (2023–2023)Yuanyuan Chen · Sun Yat-sen University Cancer Center2 papers (2023–2023)Jing Jin · Zhejiang Chinese Medical University2 papers (2023–2023)Hang Wang · Fujian Medical University2 papers (2023–2023)Jianming Cai · Wenzhou Medical University2 papers (2023–2023)Zhipeng Du · Wenzhou Medical University2 papers (2023–2023)Fangxiao Zhang · Wenzhou Medical University2 papers (2023–2023)