Area of research
Molecular Biology · Computational Theory and Mathematics
Research interest
Research interests include Computational Drug Discovery Methods, Cancer Genomics and Diagnostics, Genetics, Bioinformatics, and Biomedical Research, and Bioinformatics and Genomic Networks.
Biolink Model: A universal schema for knowledge graphs in clinical, biomedical, and translational science
Biolink Model: A universal schema for knowledge graphs in clinical, biomedical, and translational science.
Progress toward a universal biomedical data translator
Progress toward a universal biomedical data translator.
An expanded universe of cancer targets
Plasticity of ether lipids promotes ferroptosis susceptibility and evasion
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis
A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9
High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases
DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with <i>In Silico</i> Analysis to Identify Novel Therapeutic Targets
Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset
High-Throughput Luminescent Reporter of Insulin Secretion for Discovering Regulators of Pancreatic Beta-Cell Function
Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics
Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors
Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells
Quantitative-Proteomic Comparison of Alpha and Beta Cells to Uncover Novel Targets for Lineage Reprogramming
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells
Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway
Identification of Regulators of Polyploidization Presents Therapeutic Targets for Treatment of AMKL