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Magda Babina

Humboldt-Universität zu Berlin · DE
Area of research
Immunology · Immunology and Allergy
Research interest
Research interests include Mast cells and histamine, Asthma and respiratory diseases, Food Allergy and Anaphylaxis Research, and Allergic Rhinitis and Sensitization.
h-index
37
citations
8,084
works
172
NIH funding
primary concept
email

Recent publications

TNF-α counters skin inflammation by restraining mast cell–dependent thymic stromal lymphopoietin production
Journal of Allergy and Clinical Immunology 2025cited by 9position: lastdoi
Mast cells express IL17A, IL17F and RORC in lesional psoriatic skin, are activated before therapy and persist in high numbers in a resting state with IL-17A positivity after treatment
Journal of Dermatological Science 2025cited by 5position: middledoi
MRGPRX2 ligandome: Molecular simulations reveal three categories of ligand-receptor interactions
Journal of Structural Biology 2025cited by 4position: middledoi
Mast cells modulate macrophage biology through release of prestored CSF1
Journal of Allergy and Clinical Immunology 2025cited by 4position: middledoi
Prolonged <scp>IL</scp> ‐33 Exposure Switches the Secreted Mast Cell Cytokine Profile From Pro‐Inflammatory to Pro‐Tolerant
Allergy 2025cited by 3position: middledoi
Icatibant Acts as a Balanced Ligand of MRGPRX2 in Human Skin Mast Cells
Biomolecules 2025cited by 2position: lastdoi
A Novel Cell Culture System to Improve MRGPRX2 Research in Human Skin Mast Cells
Clinical and Translational Allergy 2025cited by 1position: lastdoi
Cultures of Human Skin Mast Cells, an Attractive In Vitro Model for Studies of Human Mast Cell Biology
Cells 2024cited by 7position: middledoi
Intrinsic Regulatory Mechanisms Protect Human Skin Mast Cells from Excessive MRGPRX2 Activation: Paucity in LAD2 (Laboratory of Allergic Diseases 2) Cells Contributes to Hyperresponsiveness of the Mast Cell Line
Journal of Investigative Dermatology 2024cited by 5position: lastdoi
Tolerance induction through early feeding to prevent food allergy in infants and children with sensitization against food allergens (TIFFANI): rationale, study design, and methods of a randomized controlled trial
Trials 2024cited by 2position: middledoi
CREB Is Critically Implicated in Skin Mast Cell Degranulation Elicited via FcεRI and MRGPRX2
Cells 2024cited by 2position: lastdoi
<scp>IL</scp>‐1α/β and <scp>IL</scp>‐18 profiles and their impact on claudin‐1, loricrin and filaggrin expression in patients with atopic dermatitis
Journal of the European Academy of Dermatology and Venereology 2023cited by 15position: middledoi
CREB Is Activated by the SCF/KIT Axis in a Partially ERK-Dependent Manner and Orchestrates Survival and the Induction of Immediate Early Genes in Human Skin Mast Cells
International Journal of Molecular Sciences 2023cited by 14position: lastdoi
Clorfl86/RHEX Is a Negative Regulator of SCF/KIT Signaling in Human Skin Mast Cells
Cells 2023cited by 10position: lastdoi
Synergism between IL-33 and MRGPRX2/FcεRI Is Primarily Due to the Complementation of Signaling Modules, and Only Modestly Supplemented by Prolonged Activation of Selected Kinases
Cells 2023cited by 5position: lastdoi
CREB Is Indispensable to KIT Function in Human Skin Mast Cells—A Positive Feedback Loop between CREB and KIT Orchestrates Skin Mast Cell Fate
Cells 2023cited by 4position: lastdoi
68 EVO756 is a novel MRGPRX2 antagonist that potently inhibits human mast cell degranulation in response to multiple agonists – potential treatment for CSU and beyond
Journal of Investigative Dermatology 2023cited by 2position: middledoi
MRGPRX2-Mediated Degranulation of Human Skin Mast Cells Requires the Operation of Gαi, Gαq, Ca++ Channels, ERK1/2 and PI3K—Interconnection between Early and Late Signaling
Cells 2022cited by 40position: lastdoi
MRGPRX2 in drug allergy: What we know and what we do not know
Journal of Allergy and Clinical Immunology 2022cited by 33position: middledoi
FcεRI‐ and MRGPRX2‐evoked acute degranulation responses are fully additive in human skin mast cells
Allergy 2022cited by 32position: firstdoi
Mast cells instruct keratinocytes to produce thymic stromal lymphopoietin: Relevance of the tryptase/protease-activated receptor 2 axis
Journal of Allergy and Clinical Immunology 2022cited by 30position: lastdoi
β-arrestin-1 and β-arrestin-2 Restrain MRGPRX2-Triggered Degranulation and ERK1/2 Activation in Human Skin Mast Cells
Frontiers in Allergy 2022cited by 27position: lastdoi
Serological profiling reveals hsa-miR-451a as a possible biomarker of anaphylaxis
JCI Insight 2022cited by 26position: middledoi
How “Neuronal” Are Human Skin Mast Cells?
International Journal of Molecular Sciences 2022cited by 25position: firstdoi
The <scp>SCF</scp>/<scp>KIT</scp> axis in human mast cells: Capicua acts as potent <scp>KIT</scp> repressor and <scp>ERK</scp> predominates <scp>PI3K</scp>
Allergy 2022cited by 19position: lastdoi
An interdisciplinary approach to characterize peanut‐allergic patients—First data from the FOOD@ consortium
Clinical and Translational Allergy 2022cited by 15position: middledoi
Tolerance induction through early feeding to prevent food allergy in infants with eczema (TEFFA): rationale, study design, and methods of a randomized controlled trial
Trials 2022cited by 12position: middledoi
Tolerance induction through non-avoidance to prevent persistent food allergy (TINA) in children and adults with peanut or tree nut allergy: rationale, study design and methods of a randomized controlled trial and observational cohort study
Trials 2022cited by 12position: middledoi
Cytokines Stimulated by IL-33 in Human Skin Mast Cells: Involvement of NF-κB and p38 at Distinct Levels and Potent Co-Operation with FcεRI and MRGPRX2
International Journal of Molecular Sciences 2021cited by 52position: lastdoi
Thymic Stromal Lymphopoietin Promotes MRGPRX2-Triggered Degranulation of Skin Mast Cells in a STAT5-Dependent Manner with Further Support from JNK
Cells 2021cited by 41position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

Torsten Zuberbier · Berlin Institute of Health at Charité - Universitätsmedizin Berlin19 papers (2017–2025)Kristin Franke · Humboldt-Universität zu Berlin18 papers (2019–2025)Gürkan Bal · Humboldt-Universität zu Berlin10 papers (2022–2025)Margitta Worm · Charité - Universitätsmedizin Berlin8 papers (2020–2025)Zhuoran Li · Howard Hughes Medical Institute7 papers (2022–2025)Jean Schneikert · Humboldt-Universität zu Berlin5 papers (2023–2025)Zhao Wang · Second Affiliated Hospital of Xi'an Jiaotong University5 papers (2018–2021)Sven Guhl · Humboldt-Universität zu Berlin5 papers (2017–2022)Metin Artuc · Charité - Universitätsmedizin Berlin5 papers (2017–2022)Sabine Dölle · Humboldt-Universität zu Berlin4 papers (2022–2024)Stephanie F. Heller · Mayo Clinic3 papers (2022–2024)Kirsten Beyer · Humboldt-Universität zu Berlin3 papers (2022–2024)Lara Meixner · Charité - Universitätsmedizin Berlin3 papers (2022–2024)Davender Redhu · Humboldt-Universität zu Berlin3 papers (2022–2025)Stefan Frischbutter · Humboldt-Universität zu Berlin3 papers (2020–2023)Susanne Lau · Zimmer Biomet (Germany)3 papers (2022–2024)Birgit Kalb · Charité - Universitätsmedizin Berlin3 papers (2022–2024)Marcus Maurer · McGill University3 papers (2020–2023)Shiva Raj Tripathi · Humboldt-Universität zu Berlin3 papers (2023–2024)Pavel Kolkhir · Humboldt-Universität zu Berlin3 papers (2020–2025)