Area of research
Immunology · Oncology
Research interest
Research interests include Immune Cell Function and Interaction, T-cell and B-cell Immunology, Immunotherapy and Immune Responses, and interferon and immune responses.
Evolving roles of CD38 metabolism in solid tumour microenvironment.
IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor
IL-2 regulates tumor-reactive CD8<sup>+</sup> T cell exhaustion by activating the aryl hydrocarbon receptor.
The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression.
Direct inhibitory effect on viral entry of influenza A and SARS-CoV-2 viruses by azithromycin.
Combinatorial screening of a panel of FDA-approved drugs identifies several candidates with anti-Ebola activities.
Targeting the tumor microenvironment to overcome immune checkpoint blockade therapy resistance.
Tissue-specific deconvolution of immune cell composition by integrating bulk and single-cell transcriptomes.
Azithromycin Protects against Zika Virus Infection by Upregulating Virus-Induced Type I and III Interferon Responses
Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation
Azithromycin Protects against Zika virus Infection by Upregulating virus-induced Type I and III Interferon Responses.
Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation.
Inhibition of Influenza A Virus Replication by TRIM14 via Its Multifaceted Protein-Protein Interaction With NP.
Concomitant type I IFN and M-CSF signaling reprograms monocyte differentiation and drives pro-tumoral arginase production.
Noncanonical Role of FBXO6 in Regulating Antiviral Immunity.
Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation
CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade
STAT3/p53 pathway activation disrupts IFN-β–induced dormancy in tumor-repopulating cells
Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses
Identification of TRIM14 as a Type I IFN-Stimulated Gene Controlling Hepatitis B Virus Replication by Targeting HBx
25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model
Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice
Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication
TRIM14 inhibits hepatitis C virus infection by SPRY domain-dependent targeted degradation of the viral NS5A protein
The antioxidative potential of farrerol occurs via the activation of Nrf2 mediated HO-1 signaling in RAW 264.7 cells
Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
Interferon-Inducible Cholesterol-25-Hydroxylase Inhibits Hepatitis C Virus Replication via Distinct Mechanisms