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Malcolm G. Dunlop

Western General Hospital ·
Area of research
Oncology · Pathology and Forensic Medicine
Research interest
Research interests include Colorectal Cancer Screening and Detection, Genetic factors in colorectal cancer, Gut microbiota and health, and Genetic Associations and Epidemiology.
h-index
90
citations
36,458
works
672
NIH funding
primary concept
email

Recent publications

Loss of colonic fidelity enables multilineage plasticity and metastasis
Nature 2025cited by 21position: middledoi
Impact of ambient air pollution on colorectal cancer risk and survival: insights from a prospective cohort and epigenetic Mendelian randomization study
EBioMedicine 2024cited by 57position: middledoi
Altered DNA methylation within DNMT3A, AHRR, LTA/TNF loci mediates the effect of smoking on inflammatory bowel disease
Nature Communications 2024cited by 34position: middledoi
Exposure to air pollution increases susceptibility to ulcerative colitis through epigenetic alterations in CXCR2 and MHC class III region
EBioMedicine 2024cited by 22position: middledoi
Systematic investigation of genetically determined plasma and urinary metabolites to discover potential interventional targets for colorectal cancer
JNCI Journal of the National Cancer Institute 2024cited by 19position: middledoi
Global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019
BMJ Oncology 2023cited by 265position: middledoi
Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome
Genome Medicine 2023cited by 174position: middledoi
The Contribution of Genetic Risk and Lifestyle Factors in the Development of Adult-Onset Inflammatory Bowel Disease: A Prospective Cohort Study
The American Journal of Gastroenterology 2023cited by 105position: middledoi
Dissecting the pathogenic effects of smoking and its hallmarks in blood DNA methylation on colorectal cancer risk
British Journal of Cancer 2023cited by 25position: middledoi
Alcohol consumption, <scp>DNA</scp> methylation and colorectal cancer risk: Results from pooled cohort studies and Mendelian randomization analysis
International Journal of Cancer 2022cited by 74position: middledoi
Characteristics of Early-Onset vs Late-Onset Colorectal Cancer
JAMA Surgery 2021cited by 284position: middledoi
Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation
eLife 2021cited by 43position: middledoi
Genetically predicted physical activity levels are associated with lower colorectal cancer risk: a Mendelian randomisation study
British Journal of Cancer 2021cited by 39position: middledoi
Risk factors and risk prediction models for colorectal cancer metastasis and recurrence: an umbrella review of systematic reviews and meta-analyses of observational studies
BMC Medicine 2020cited by 175position: middledoi
Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases
Science Advances 2020cited by 138position: middledoi
Systematic Evaluation of Normalization Methods for Glycomics Data Based on Performance of Network Inference
Metabolites 2020cited by 21position: middledoi
British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults
Gut 2019cited by 2,298position: middledoi
Genetic predisposition to mosaic Y chromosome loss in blood
Nature 2019cited by 336position: middledoi
Modifiable pathways for colorectal cancer: a mendelian randomisation analysis
˜The œLancet. Gastroenterology & hepatology 2019cited by 135position: middledoi
Defining the genetic control of human blood plasma N-glycome using genome-wide association study
Human Molecular Genetics 2019cited by 63position: middledoi
Head-to-Head Comparison of Family History of Colorectal Cancer and a Genetic Risk Score for Colorectal Cancer Risk Stratification
Clinical and Translational Gastroenterology 2019cited by 4position: middledoi
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels
Nature Communications 2018cited by 396position: middledoi
Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases
Gastroenterology 2018cited by 161position: middledoi
Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study
BMC Medicine 2018cited by 80position: lastdoi
Coding variants in NOD-like receptors: An association study on risk and survival of colorectal cancer
PLoS ONE 2018cited by 11position: middledoi
Establishing Key Performance Indicators [KPIs] and Their Importance for the Surgical Management of Inflammatory Bowel Disease–Results From a Pan-European, Delphi Consensus Study
Journal of Crohn s and Colitis 2017cited by 36position: middledoi
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease
Nature Communications 2016cited by 272position: middledoi
Five endometrial cancer risk loci identified through genome-wide association analysis
Nature Genetics 2016cited by 96position: middledoi
Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer
British Journal of Cancer 2016cited by 75position: middledoi
Correspondence: SEMA4A variation and risk of colorectal cancer
Nature Communications 2016cited by 9position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Evropi Τheodoratou · University of Edinburgh11 papers (2020–2024)Xue Li · Department of Health11 papers (2020–2024)Richard S. Houlston · Institute of Cancer Research9 papers (2014–2024)Susan M. Farrington · Western General Hospital9 papers (2014–2024)Philip Law · Johns Hopkins Medicine7 papers (2019–2024)Jing Sun · Tongji University7 papers (2022–2024)Shuai Yuan · University of Hawaiʻi at Mānoa7 papers (2022–2024)Lijuan Wang · Capital Medical University6 papers (2022–2024)Jianhui Zhao · Union Hospital6 papers (2023–2024)Ian Tomlinson · Science Oxford5 papers (2014–2021)Kefeng Ding · Ministry of Education of the People's Republic of China5 papers (2022–2023)Susanna C. Larsson · Karolinska Institutet5 papers (2023–2024)Jie Chen · Central South University4 papers (2023–2024)Xuan Zhou · University of Edinburgh4 papers (2022–2024)Asta Försti · German Cancer Research Center3 papers (2014–2018)Michael Hoffmeister · Festo (Germany)3 papers (2018–2019)Lili Yu · Guangzhou University of Chinese Medicine3 papers (2022–2023)Hermann Brenner · Stanford University3 papers (2018–2019)Rahul Kalla · NHS Lothian3 papers (2023–2024)Kari Hemminki · Lund University3 papers (2014–2018)