Area of research
Physiology · Cellular and Molecular Neuroscience
Research interest
Research interests include Alzheimer's disease research and treatments, Neuroscience and Neuropharmacology Research, Nuclear Receptors and Signaling, and Parkinson's Disease Mechanisms and Treatments.
Tau protein profiling in tauopathies: a human brain study
PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins
Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo
Learnings about the complexity of extracellular tau aid development of a blood‐based screen for Alzheimer's disease
Characterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathy
Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures
Dietary (−)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing
AMPA Receptor Activation Promotes Non-Amyloidogenic Amyloid Precursor Protein Processing and Suppresses Neuronal Amyloid-β Production